Department of Clinical Biochemistry and Pharmacology

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• MicroRNAs as Biomarkers of Obesity Sub-Phenotypes and as Mediators of Obesity-Related Liver Metabolic Dysfunction

  Makarenkov, N. (Author), Rudich, A. (Supervisor) & Veksler-Lublinsky, I. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Re-Analysis of Genome-Wide Association Studies to Reduce the Missing Heritability Gap in Neurodegenerative Disorders

  Thangathurai, K. (Author), Rubin, E. (Supervisor), Engel, S. (Supervisor) & Rappoport, N. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Applying Computational Methods for Illuminating Molecular Mechanisms Than Govern Genotype-Phenotype Relationships

  Jubran, J. (Author), Yeger-Lotem, E. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Analyses of Cellular Systems Associated with Autophagy and Proteostasis Regulation in Tissues and Cell Types in Human

  Talyah, E. (Author), Yeger-Lotem, E. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Cellular Transport Mechanisms Regulate Succinate Homeostasis and and its Delivery into Macrophages to Control Their Inflammatory State

  Fremder, M. (Author), Ohana, E. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Mechanisms for the Protective Effect of Carotenoids, Polyphenols and estradiol in Human Primary Skin Cells Under Mitochondrial Oxidative Stress

  Darawshe, A. (Author), Sharoni, Y. (Supervisor), Ben-Shabat, S. (Supervisor) & Danilenko, M. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Roles of Glutathione and AP-1 in the Enhancement of Vitamin D-induced Differentiation by Activators of the Nrf2 Signaling Pathway in Acute Myeloid Leukemia Cells

  Jramne, Y. (Author), Danilenko, M. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Complexes of Metabolite Transporters Orchestrate the Homeostasis of Krebs Cycle Intermediates and Cellular Bioenergetics

  Khamaysi, A. (Author), Ohana, E. (Supervisor), 2024

  Student thesis: Doctoral Thesis

• Developing Computational Approaches for Illuminating Disease Mechanisms Using Omics Data

  Argov, C. M. (Author), Yeger-Lotem, E. (Supervisor), 2023

  Student thesis: Doctoral Thesis

• Blocking the Pathogenic B6/B7-Loop Epitope of Misfolded SOD1: a Steategy for ALS Treatment

  Bakavayev, S. (Author), Israelson, A. (Supervisor) & Engel, S. (Supervisor), 2023

  Student thesis: Doctoral Thesis

• Biomedical Copolymers to Target Strategic Molecules in the Tumor Microenvironment for Inhibition of Tumor Growth and Site-Specific Drug Delivery

  Ruetter, M. (Author), David, A. (Supervisor), 2023

  Student thesis: Doctoral Thesis

• The Effect of Combinations of Carotenoids and Polyphenols on Bone Remodeling in a 3D Construct of Mineralized Bone in Modeled Microgravity

  Nimer, A. (Author), Sharoni, Y. (Supervisor) & Danilenko, M. (Supervisor), 2023

  Student thesis: Doctoral Thesis

• Alpha1-Antitrypsin Protects Pancreatic Islets from Dexamethasone, a Diabetogenic Drug, Study of Mechanism of Action

  Motola, N. (Author), Lewis, E. (Supervisor), 2023

  Student thesis: Doctoral Thesis

• Identification and Comprehension of Physiological and Pathological Mechanisms Using Large-Scale Data and Molecular Characterization of Human Tissues

  Hekselman Toledano, I. (Author), Yeger-Lotem, E. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• Applying Computational and Machine Learning Methods toward Large Scale Analysis of Biological Data

  Sharon, M. (Author), Yeger-Lotem, E. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• The Relationship Between the Serin-Protease Inhibitor, Alpha-1 Antitrypsin and Hematopoietic Stem-Cell Transplantation, and its Role in Graft-Versus-Host-Disease Pathophysiology

  Brami, I. H. (Author), Lewis, E. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• An E2F1-mRNA-miRNA Network in Visceral Adipose Tissue as a Molecular Signature of an Adverse Immune-Metabolic Obese Sub-phenotype

  Maixner, N. (Author), Rudich, A. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• Oral Delivery of Lipophilic Drugs: The Solubility-Permeability Interplay and Optimal Formulation Design

  Fine Shamir, N. (Author), Dahan, A. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• Directed Evolution to Engineer Improved Proteins for Structural Studies and Drug Discovery ? Two Case Studies of the Method:Ligand and Receptor

  Meltzer, M. (Author), Papo, N. (Supervisor) & Engel, S. (Supervisor), 2022

  Student thesis: Doctoral Thesis

• Influence of Doxorubicin Liposomes Surface Groups on Drug Disposition, and the Balance of its Pharmacological Effects

  Popilski, H. (Author), Stepensky, D. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Structural and Functional Aspects of Alpha1-Antitrypsin: Identification of Non-Canonical Surface Loci and Domains for Biological Function Optimization

  Lior, Y. (Author), Lewis, E. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• "Drug-Free" Polymer Conjugates for Inhibition of Neutrophil Trafficking into Inflamed Tissues

  Milosevic, N. (Author), David, A. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Non Pigmented Ciliary Epithelium Exosomes' Role as Signaling Mediators Within the Ocular Drainage System for a Better Understanding of Glaucoma Pathology

  Tabak, S. (Author), Schreiber-Avissar, S. S. (Supervisor) & Beit - Yannai, E. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Drug Targeting Strategy for the Treatment of Inflammatory Bowel Disease: a Novel Phospholipid-based Prodrug Approach

  Markovic, M. (Author), Dahan, A. (Supervisor) & Ben-Shabat, S. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Targeting Survival Pathways by Synergistically Acting Plant Polyphenol Combinations in Translational Models of Acute Myeloid Leukemia

  Trachtenberg, A. (Author), Danilenko, M. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Mechanism of Calcium-Mediated Apoptosis Induction by Combinations of Plant Phenolic Compounds in Acute Myeloid Leukemia Cells

  Muduli, S. (Author), Danilenko, M. (Supervisor), 2021

  Student thesis: Doctoral Thesis

• Role of Liver miRNAs in the Rapid Resolution of Obesity-Associated Dysglycemia and Fatty Liver

  Vatarescu, M.-H. (Author), Rudich, A. (Supervisor), 2020

  Student thesis: Doctoral Thesis

• Circadian Rhythm Disturbances, Depression and Type 2 Diabetes

  Bilu, C. (Author), Agam, G. (Supervisor) & Azab, A. N. (Supervisor), 2020

  Student thesis: Doctoral Thesis

• Harnessing Human Tissue Transcriptomes and Machine Learning Methods for Obtaining Biological and Clinical Insights

  Simonovsky, E. (Author), Yeger-Lotem, E. (Supervisor), 2020

  Student thesis: Doctoral Thesis

• CD44-Targeted Polymer-Drug Conjugates and "Drug Free" Copolymers for the Control of the Spread and Growth of Metastatic Tumors

  Zaiden, M. (Author), David, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Modulation of Brain Inflammation by Angiotensin Related Drugs

  Nadiv, N. (Author), Sigal, F.-B. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Regulation of Brain Inflammation by Neuropeptides ? in vivo and in vitro Models

  Marin-Asraf, K. (Author), Sigal, F.-B. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Mechanism of Islet Xenograft Protection by Combined Temporary T Cell Depletion and ?1-antitrypsin Therapy

  Baranovski, B. (Author), Lewis, E. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Network Biology Approaches to Decipher Biological Pathways in Genetic Disorders

  Basha, O. (Author), Birk, O. (Supervisor) & Yeger-Lotem, E. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Regional-Dependent Intestinal Absorption after Oral Administration and its Impact on Regulatory Approval of Generic Drug Products

  Fairstein-Zur, M. (Author), Agbaria, R. (Supervisor) & Dahan, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Non-Pigmented Ciliary Epithelium Derived Exosomes and Their Role within the Drainage System as a Pharmacological Intervention Target for Glaucoma

  Lerner, N. A. (Author), Schreiber-Avissar, S. S. (Supervisor) & Beit - Yannai, E. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Autophagy in Adipose Tissue Macrophages and its Contribution to Adipose Tissue Dysfunction in Obesity

  Hadadi, S. (Author), Rudich, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Non-Pigmented Ciliary Epithelium Derived Exosomes and Their Role within the Drainage System as a Pharmacological Intervention Target for Glaucoma

  Lerner, N. A. (Author), Beit - Yannai, E. (Supervisor) & Schreiber-Avissar, S. S. (Supervisor), 2019

  Student thesis: Doctoral Thesis

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• Immune Cells (Macrophages, Mast Cells), Adipo-cytokines and Autophagy in Adipose Tissue in Obesity

  Goldstein, N. (Author), Rudich, A. (Supervisor), 2019

  Student thesis: Doctoral Thesis

• Mechanism of Alpha-1-antitrypsin in Promoting Wound Healing Process

  Schuster, R. (Author), Lewis, E. (Supervisor), 2018

  Student thesis: Doctoral Thesis

• Metabolic Reprogramming of Adipose Tissue Macrophages in Obesity

  Pacht, T. (Author), Rudich, A. (Supervisor), 2018

  Student thesis: Doctoral Thesis

• Topological Pattern Discovery in Biological Systems and its Applications

  Smoly, I. (Author), Ziv-Ukelson, M. (Supervisor) & Yeger-Lotem, E. (Supervisor), 2017

  Student thesis: Doctoral Thesis

• The Solubility-Permeability Interplay and Its Implication for Oral Delivery of Lipophilic Drugs

  Beig, A. (Author), Agbaria, R. (Supervisor) & Dahan, A. (Supervisor), 2017

  Student thesis: Doctoral Thesis

• Study of the Mechanism behind the Bacterial-load Reducing Activity of a -1- Antitrypsin

  Kaner, Z. (Author), Lewis, E. (Supervisor), 2017

  Student thesis: Doctoral Thesis

• Deciphering the Etiology of Hereditary Diseases by Using Tissue-Specific Molecular Networks

  Barshir, R. (Author), Yeger-Lotem, E. (Supervisor), 2016

  Student thesis: Doctoral Thesis

• Context-Dependent Duality in Immunomodulation: The Role of alfa1-antitrypsin in Autoimmune Diabetes and Cancer Immunology

  Guttman, O. (Author), Lewis, E. (Supervisor), 2016

  Student thesis: Doctoral Thesis

• Involvement of Adenosine in The Escape of Cancer Cells from Immune Surveillance

  Eini Raider, H. (Author), Lewis, E. (Supervisor) & Douvdevani, A. (Supervisor), 2013

  Student thesis: Doctoral Thesis