Research output per year
Research output per year
Personal profile
Research interests
Prof. David's research integrates polymer chemistry, molecular biology, pharmacology, and biomedical engineering to design innovative therapeutic polymers and nanomedicines for targeted drug delivery, aiming to treat diseases such as cancer, cardiovascular conditions, and liver diseases. Her lab develops polymers that can either bind to disease-specific molecules or adapt their properties at target tissues in response to local stimuli. This interdisciplinary approach supports translational research for precision medicine.
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Dive into the research topics where Ayelet David is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Mesoporous Silica Nanoparticles with Extra-Large Pores for Boosting Antigen Presentation and PD-L1 Immune Checkpoint Blockade
Srivastava, P., Rütter, M., Antoniraj, G. M., Ventura, Y. & David, A., 17 Nov 2025, In: ACS Applied Bio Materials. 8, 11, p. 9864-9874 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury
Milošević, N., Rütter, M., Ventura, Y., Feinshtein, V. & David, A., 1 Jan 2025, In: Pharmaceutics. 17, 1, 82.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Dendritic Cell-Targeted Nanoparticles Enhance T Cell Activation and Antitumor Immune Responses by Boosting Antigen Presentation and Blocking PD-L1 Pathways
Srivastava, P., Rütter, M., Antoniraj, G., Ventura, Y. & David, A., 9 Oct 2024, In: ACS Applied Materials and Interfaces. 16, 40, p. 53577-53590 14 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
E-selectin-targeted polymer-doxorubicin conjugate induces regression of established colorectal liver metastases and improves mice survival
Rütter, M., Milošević, N., Ventura, Y., Feinshtein, V. & David, A., 1 Apr 2024, In: Nano Today. 55, 102182.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines
Milošević, N., Rütter, M. & David, A., 1 Jan 2022, In: Frontiers in Medical Technology. 4, 846065.Research output: Contribution to journal › Review article › peer-review
Open Access35 Scopus citations -
Say no to drugs: Bioactive macromolecular therapeutics without conventional drugs
Rütter, M., Milošević, N. & David, A., 10 Feb 2021, In: Journal of Controlled Release. 330, p. 1191-1207 17 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Attenuation of neutrophil-mediated liver injury in mice by drug-free E-selectin binding polymer
Milošević, N., Rütter, M., Ventura, Y., Kezerle, Y., Feinshtein, V. & David, A., 10 Mar 2020, In: Journal of Controlled Release. 319, p. 475-486 12 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
David, A. (Inventor), Ashkenasy, G. (Inventor) & Shamay, Y. (Inventor), 25 Jul 2019, IPC No. A61K 49/ 00 A I, Patent No. US2019225653, Priority date 30 Nov 2018, Priority No. US201816205275Research output: Patent
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Near-Infrared Fluorescent Activated Polymeric Probe for Imaging Intraluminal Colorectal Cancer Tumors
Kopansky-Groisman, E., Kogan-Zviagin, I., Sella-Tavor, O., Oron-Herman, M. & David, A., 9 Sep 2019, In: Biomacromolecules. 20, 9, p. 3547-3556 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
CD44-Targeted Polymer-Paclitaxel Conjugates to Control the Spread and Growth of Metastatic Tumors
Zaiden, M., Rütter, M., Shpirt, L., Ventura, Y., Feinshtein, V. & David, A., 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 3690-3699 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations
Press/Media
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Ben-Gurion University of the Negev Researchers Describe Advances in Acute Kidney Injury (Targeted Polymer-Peptide Conjugates for E-Selectin Blockade in Renal Injury)
Ruetter, M. & David, A.
7/02/25
1 item of Media coverage
Press/Media
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Live-cell analysis to visualize, quantify and monitor cell proliferation and death
David, A. (PI)
1/01/25 → …
Project: Research
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Peptide-Polymer Conjugates to Control Cancer Metastasis by Activating Effector NK and T Cells
David, A. (PI)
1/01/25 → 31/12/29
Project: Research
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Imaging-based evaluation and therapy of heart failure with preserved ejection fraction
Leor, J. (PI), Epstein, F. F. (CoPI) & David, A. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/17 → …
Project: Research
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A New Polymer-Drug Combination Therapy for Targeting Ovarian Cancer
Kopecek, J. J. (PI) & David, A. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/07 → …
Project: Research
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Refractive Index Detector and Light Scattering Detector Flow Cytometer Tissue culture facility
David, A. (PI)
1/01/07 → …
Project: Research
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Drug-free multivalent biopolymers to detect and prevent outgrowth of metastases
David, A. (PI)
1/01/19 → 31/12/23
Project: Research
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Drug-free multivalent biopolymers to detect and prevent outgrowth of metastases
David, A. (PI)
1/01/19 → 31/12/23
Project: Research
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E-SELECTIN TARGETED POLYMER CONJUGATES FOR TREATING PROSTATE CANCER TUMORS AND BONE METASTASIS
David, A. (PI)
1/01/16 → 31/12/18
Project: Research
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Targeted Polymer-Drug Conjugates for Manipulating Tumor Vascular Endothelial Cell Death
David, A. (PI)
1/01/10 → 31/12/13
Project: Research
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Sialyl Lewis(x)-polymer conjugates for targeting chemotherapeutic drugs to tumor vascular endothelium
David, A. (PI)
1/01/07 → 31/12/09
Project: Research