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Collaborations and top research areas from the last five years
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ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells
Abaev-Schneiderman, E., Nguyen, L., Shalev, R., Biton, T. E., Chopra, A., Jagadeesan, G., Sevilla-Sanchez, D., Moskovitz, N. T., Levin, L., Feldman, M., Van Rechem, C. & Levy, D., 1 Jan 2026, In: Genome Research. 36, 4, p. 684-694 11 p.Research output: Contribution to journal › Article › peer-review
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E2F1 K117 methylation by SETD6 disrupts BRD4–E2F1 binding and modulates E2F1 chromatin binding and gene regulation in prostate cancer cells
Ulu, G. T., Kublanovsky, M., Shalev, R., Biton, T. E., Feldman, M., Murr, S., Brockmeyer, J., Dorscht, F., Weirich, S., Levy, D. & Jeltsch, A., 27 Jan 2026, In: Nucleic Acids Research. 54, 2, gkaf1513.Research output: Contribution to journal › Article › peer-review
Open Access -
A ciliopathy combining Joubert syndrome and Oro-Facial-Digital syndrome caused by bi-allelic 5’-UTR loss-of-function CEP83 variant
Jean, M. M., Yunis, A., Elbaz-Biton, T., Dolgin, V., Narkis, G., Michaelovsky, A., Eskin-Schwartz, M., Tsitrina, A. A., Agam, N., Poleg, T., Safran, A., Freund, O., Hadar, N., Levy, D., Shelef, I., El Amour, K., Flusser, H. & Birk, O. S., 1 Dec 2025, In: npj Genomic Medicine. 10, 1, 66.Research output: Contribution to journal › Article › peer-review
Open Access -
Machine learning-driven prediction of substrates for enzymes introducing or removing protein post-translational modifications
Ridgeway, N. H., Chopra, A., Lukinović, V., Feldman, M., Charih, F., Levy, D., Green, J. R. & Biggar, K. K., 1 Dec 2025, In: Communications Chemistry. 8, 1, 340.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Mechanisms of Substrate Recognition by the Multispecific Protein Lysine Methyltransferase SETD6
Ulu, G. T., Weirich, S., Kehl, J., Chandrasekaran, T. T., Dorscht, F., Levy, D. & Jeltsch, A., 1 Oct 2025, In: Life. 15, 10, 1578.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Orchestrating epigenetics: a comprehensive review of the methyltransferase SETD6
Chopra, A., Feldman, M. & Levy, D., 1 Mar 2025, In: Experimental and Molecular Medicine. 57, 3, p. 533-544 12 p., 377.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
RAD18 methylation by the methyltransferase SETD6 attenuates DNA breaks
Weil, L. E., Feldman, M., Van Duine, J., Qiu, J., LaBaer, J. & Levy, D., 1 Dec 2025, In: Scientific Reports. 15, 1, 31643.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
SETD6 mediates selective interaction and genomic occupancy of BRD4 and MITF in melanoma cells
Biton, T. E., Feldman, M., Davidy, T., Moskovitz, N. T., Levin, L., Sevilla, D., Goding, C. R., Bernstein, E. & Levy, D., 1 Sep 2025, In: NAR Cancer. 7, 3, zcaf023.Research output: Contribution to journal › Article › peer-review
Open Access -
SUMO-mediated regulation of H3K4me3 reader SET-26 controls germline development in C. elegans
Carvalho, C. A., Abu-Shach, U. B., Raju, A., Vershinin, Z., Levy, D., Boxem, M. & Broday, L., 1 Jan 2025, In: PLOS Biology. 23, 1, e3002980.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Distinct specificities of the HEMK2 protein methyltransferase in methylation of glutamine and lysine residues
Weirich, S., Ulu, G. T., Chandrasekaran, T. T., Kehl, J., Schmid, J., Dorscht, F., Kublanovsky, M., Levy, D. & Jeltsch, A., 1 Feb 2024, In: Protein Science. 33, 2, e4897.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations
Press/Media
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Researchers at Ben-Gurion University of the Negev Report Findings in Prostate Cancer (E2F1 K117 methylation by SETD6 disrupts BRD4-E2F1 binding and modulates E2F1 chromatin binding and gene regulation in prostate cancer cells)
Levy, D., Elbaz Biton, T. & Shalev, R.
3/02/26
1 item of Media coverage
Press/Media
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Studies from Ben-Gurion University of the Negev Have Provided New Data on Melanoma (SETD6 mediates selective interaction and genomic occupancy of BRD4 and MITF in melanoma cells)
Levy, D., Elbaz Biton, T., Levin, L. & Tickotsky Moskovitz, N. B.
27/08/25
1 item of Media coverage
Press/Media
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SETD6 mediated lysine methylation of PPARγ in the regulation of lipid droplet formation and steatosis
Levy, D. (PI)
1/01/23 → 31/12/27
Project: Research
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SETD6 mediated lysine methylation of PPARγ in the regulation of lipid droplet formation and steatosis
Levy, D. (PI)
1/01/23 → 31/12/27
Project: Research
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Role of Lysine Methylation in the Regulation of Mitotic Events under Replication Stress
Levy, D. (PI)
1/01/21 → …
Project: Research
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Dissecting lysine methylation signaling in melanoma pathobiology
Levy, D. (PI) & Bernstein, E. E. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/19 → …
Project: Research
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TWIST1 post-translational modification crosstalk in EMT
Levy, D. (PI) & Bedford, M. M. (CoPI)
1/01/19 → …
Project: Research
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TWIST1 post-translational modification crosstalk in EMT
Levy, D. (PI) & Bedford, M. M. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/19 → …
Project: Research
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NSD3's function in chromatin-mediated processes and oncogenesis
Levy, D. (CoPI) & Gozani, O. (PI)
Human Frontier Science Program
1/01/09 → …
Project: Research