Research output per year
Research output per year
Personal profile
Research interests
My lab studies genet and genomic aspects of mitochondrial functiona and evolution. We are interested in the functional potential and outcome of genetic variants, in transcriptional regulation of the mitochondrial genome, mit-nuclear co-evolution and co-regulation.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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The metazoan landscape of mitochondrial DNA gene order and content is shaped by selection and affects mitochondrial transcription
Shtolz, N. & Mishmar, D., 1 Dec 2023, In: Communications Biology. 6, 1, 93.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Universities should denounce terrorism and antisemitism
Mishmar, D., Carmel, L., Shema, E. & Falik-Zaccai, T., 16 Nov 2023, In: Nature. 623, 7987, p. 483 1 p.Research output: Contribution to journal › Comment/debate
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Coordination of mitochondrial and nuclear gene-expression regulation in health, evolution, and disease
Papier, O., Minor, G., Medini, H. & Mishmar, D., 1 Jun 2022, In: Current Opinion in Physiology. 27, 100554.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Erratum: Human primitive brain displays negative mitochondrial-nuclear expression correlation of respiratory genes (Genome Research (2018) 28 (952-967) DOI: 10.1101/gr.226324.117)
Barshad, G., Blumberg, A., Cohen, T. & Mishmar, D., 1 Aug 2022, In: Genome Research. 32, 8, p. 1626 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Human mitochondrial RNA modifications associate with tissue-specific changes in gene expression, and are affected by sunlight and UV exposure
Cohen, T., Medini, H., Mordechai, C., Eran, A. & Mishmar, D., 1 Dec 2022, In: European Journal of Human Genetics. 30, 12, p. 1363-1372 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Mutant C. Elegans Mitofusin Leads to Selective Removal of mtDNA Heteroplasmic Deletions Across Generations to Maintain Fitness
Meshnik, L., Bar-Yaacov, D., Kasztan, D., Neiger, T., Cohen, T., Kishner, M., Valenci, I., Dadon, S., Klein, C. J., Vance, J. M., Nevo, Y., Züchner, S., Ovadia, O., Mishmar, D. & Ben-Zvi, A., 9 Feb 2022, In: BMC Biology. 20, 1, 40.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis
Medini, H., Zirman, A. & Mishmar, D., 17 Dec 2021, In: iScience. 24, 12, 103471.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Mitochondrial gene expression in single cells shape pancreatic beta cells' sub-populations and explain variation in insulin pathway
Medini, H., Cohen, T. & Mishmar, D., 1 Dec 2021, In: Scientific Reports. 11, 1, 466.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Predicting 3D protein structures in light of evolution
Bershtein, S., Kleiner, D. & Mishmar, D., 22 Jul 2021, In: Nature Ecology and Evolution. 5, 9, p. 1195-1198 4 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Mitochondria Are Fundamental for the Emergence of Metazoans: On Metabolism, Genomic Regulation, and the Birth of Complex Organisms
Medini, H., Cohen, T. & Mishmar, D., 23 Nov 2020, In: Annual Review of Genetics. 54, p. 151-166 16 p.Research output: Contribution to journal › Review article › peer-review
12 Scopus citations
Equipment
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Mishmar Lab - Mitochondrial Genomics and Evolution
Mishmar, D. (PI)
Department of Life SciencesEquipment/facility: lab