Research output per year
Research output per year
Personal profile
Research interests
- Understanding the role of the COP9 signalosome (CSN) in regulating development. This is the oldest project in the lab, and probably what we're most well known for. The CSN is a multi-subunit protein complex that I originally identified in Arabidopsis, but which we later showed to be essential for animal development as well. We are using a combination of genetic, molecular and genomic approaches to dissect the varied roles of the CSN in the development of plants and animals, using both Arabidopsis and Drosophila as model systems.
- Recently we got interested in the question of what anti-cancer chemicals found in plants do for the plant. Particularly we're studying indole-3-carbinol (I3C), a phytochemical found in vegetables like broccoli and mustard that has also been reported effective in killing breast and prostate cancer cells. We are working out the mechanisms by which these chemicals modulate plant biology.
Education/Academic qualification
PhD, Molecular Analysis of the Early Steps of Carotenoid Biosynthesis in Cyanobacteria: Phytoene Synthase and Phytoene Desaturase, Hebrew University of Jerusalem
Award Date: 1 Jan 1993
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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What a Plant Knows: A Field Guide to the Senses: Updated and Expanded Edition
Chamovitz, D., 2017, Revised edition ed. New York: Scientific American/Farrar, Straus and Giroux. 224 p.Research output: Book/Report › Book › peer-review
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Investigation of the Roles of Phosphatidylinositol 4-Phosphate 5-Kinases 7,9 and Wall-Associated Kinases 1–3 in Responses to Indole-3-Carbinol and Biotic Stress in Arabidopsis Thaliana
Khamesa-Israelov, H., Finkelstein, A., Shani, E. & Chamovitz, D. A., 1 Oct 2024, In: Biomolecules. 14, 10, 1253.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Overexpression of S30 Ribosomal Protein Leads to Transcriptional and Metabolic Changes That Affect Plant Development and Responses to Stress
Finkelshtein, A., Khamesa-Israelov, H. & Chamovitz, D. A., 1 Mar 2024, In: Biomolecules. 14, 3, 319.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The Role of Science, Technology, and Innovation for Transforming Food Systems in Asia
Moughan, P. J., Chamovitz, D. A., Ayyappan, S., Tanticharoen, M., Lal, K. & Kim, Y. H., 1 Jan 2023, Science and Innovations for Food Systems Transformation. Springer International Publishing, p. 751-761 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Open Access -
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation
Malka, O., Malishev, R., Bersudsky, M., Rajendran, M., Krishnamohan, M., Shaik, J., Chamovitz, D. A., Tikhonov, E., Sultan, E., Koren, O., Apte, R. N., Rosental, B., Voronov, E. & Jelinek, R., 21 Feb 2023, In: Journal of Innate Immunity. 15, 1, p. 531-547 17 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
צמח - מה הוא יודע? עולם החושים המפתיע של הצמחים – מהדורה חדשה ומעודכנת
חיימוביץ, ד., Sep 2023, 2 ed. ישראל: מטר. 191 p. (מטר - עיון)Research output: Book/Report › Book › peer-review
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Ulvan crude extract's chemical and biophysical profile and its effect as a biostimulant on Arabidopsis thaliana
Shefer, S., Lebendiker, M., Finkelshtein, A., Chamovitz, D. A. & Golberg, A., 1 Mar 2022, In: Algal Research. 62, 102609.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
על קיימות ושינוי אקלים בפריזמה מדברית: ריאיון עם פרופ׳ דניאל חיימוביץ, נשיא אוניברסיטת בן-גוריון בנגב
בוקמן, ש. & חיימוביץ, ד., Jun 2022, In: אקולוגיה וסביבה. 13, 1, p. 76–78Research output: Contribution to journal › Article
Open Access -
Csn5a subunit of cop9 signalosome is required for resetting transcriptional stress memory after recurrent heat stress in arabidopsis
Singh, A. K., Dhanapal, S., Finkelshtein, A. & Chamovitz, D. A., 1 May 2021, In: Biomolecules. 11, 5, 668.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Overexpression of the ribosomal S30 subunit leads to indole-3-carbinol tolerance in Arabidopsis thaliana
Finkelshtein, A., Khamesa, H., Tuan, L. A., Rabanim, M. & Chamovitz, D. A., 1 Feb 2021, In: Plant Journal. 105, 3, p. 668-677 10 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Prizes
Thesis
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Molecular analysis of the early steps of carotenoid biosynthesis in cyanobacteria: phytoene synthase and phytoene desaturase
Chamovitz, D. (Author), Hirschberg, J. (Supervisor), 1993Student thesis: Doctoral Thesis
Press/Media
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Boeing, Ben-Gurion University launch Aviation Cybersecurity Center
29/01/26
2 items of Media coverage
Press/Media
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New ranking reveals which Israeli universities graduate students on time
21/01/26
2 items of Media coverage
Press/Media
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Ben-Gurion University inaugurates the Stein School of Computer and Information Science
24/12/25
1 item of Media coverage
Press/Media
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BGU bestows 7 honorary doctorates at Board of Governors meeting
15/05/25
1 item of Media coverage
Press/Media
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How one elite university figured out how to handle anti-Israel protests
Chamovitz, D. & Abu-Rabia-Queder, S.
30/04/24
2 items of Media coverage
Press/Media
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Association of University Heads, Israel: Statement on Violent Demonstrations, Antisemitism In US
27/04/24
1 item of Media coverage
Press/Media
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Top Israeli official to speak in Aspen
Chamovitz, D. & Davidovitch, N.
5/08/23
1 item of Media coverage
Press/Media
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Ben-Gurion University bestows honorary doctorates on Chelsea Clinton, Patrick Drahi, Elyakim Rubinstein and other luminaries
18/05/23
1 item of Media coverage
Press/Media
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Scientific delegation from the Ben-Gurion University of Israel will visit the Galapagos and the Ecuadorian Amazon
3/02/23
1 item of Media coverage
Press/Media
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UIR, Ben-Gurion University Vow to Strengthen Partnership in Scientific Research
11/11/22
1 item of Media coverage
Press/Media
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ZOMES VI: PCI complexes beyond the proteasome, signalosome and eiF3
Glickman, M. H. (PI) & Chamovitz, D. (CoPI)
1/01/10 → …
Project: Research
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Chemical genetics of the COP9 Signalosome and ribonucleotide reductase
Yang, Z. Z. (PI) & Chamovitz, D. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/09 → …
Project: Research
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Integration of Signaling Pathways: EIF3e and the COP9 Signalsome in Arabidopsis
Chamovitz, D. (PI) & Von, A. A. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/00 → …
Project: Research
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Molecular Analysis of the Nuclear COP9 Protein Complex
Chamovitz, D. (PI) & Von, A. A. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/96 → …
Project: Research
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The roles of the phytochemical indole-3-carbinol in mediating between plant defense responses and plant development
Chamovitz, D. (PI)
1/01/18 → 31/12/22
Project: Research
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The structure-function of the COP9 signalosome from Arabidopsis and its role in binding DNA
Chamovitz, D. (PI)
1/01/13 → 1/01/18
Project: Research
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Structure-function analysis of the COP9 signalosome from Arabidopsis
Chamovitz, D. (PI)
1/01/09 → 31/12/12
Project: Research
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Structure-function analysis of the CSN7 subunit of the COP9 signalosome
Chamovitz, D. (PI) & Hirsch, J. A. (CoPI)
1/01/05 → 31/12/08
Project: Research
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Isolation and characterization of components of the plant morphogenic transduction pathway
Chamovitz, D. (CoPI) & Deng, X. W. X. W. (PI)
Human Frontier Science Program
1/01/93 → 31/12/95
Project: Research