Personal profile
Roles and Responsibilities
Head of undergraduate teaching committee, School of Brain Sciences and Cognition, BGU
Education/Academic qualification
PhD, Molecular mechanisms underlying growth cone formation in cultured Aplysia identified neurons, Hebrew University of Jerusalem
Award Date: 1 Oct 1999
Bachelor, Biology and Computer Science, Hebrew University of Jerusalem
1989 → 1992
Keywords
- QP Physiology
- alpha-synuclein
- synapse
- neuron
- Parkinson's disease
- synapsin
- C9orf72
- FTD/ALS
- presynaptic
- glutamate
- fluorescence microscopy
- genetically encoded indicators
- QH301 Biology
Fingerprint
- 1 Similar Profiles
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ATP binding to Synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons
Shulman, Y., Stavsky, A., Fedorova, T., Mikulincer, D., Atias, M., Radinsky, I., Kahn, J., Slutsky, I. & Gitler, D., 21 Jan 2015, In: Journal of Neuroscience. 35, 3, p. 985-998 14 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Histone deacetylase SIRT6 regulates tryptophan catabolism and prevents metabolite imbalance associated with neurodegeneration
Kaluski-Kopatch, S., Stein, D., Venzor, A. G., Ferreira Campos, A. M., Planque, M., Goldstein, B., De Allende-Becerra, E., Smirnov, D., Zaretsky, A., Eremenko, E., Portillo, M., Einav, M., Krejci, A. B., Abdu, U., Khrameeva, E., Gitler, D., Fendt, S. M. & Toiber, D., 1 Dec 2026, In: Nature Communications. 17, 1, 320.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Presynaptic ATP Decreases During Physiological-Like Activity in Neurons Tuned for High-Frequency Transmission
Straub, I., Kunstmann, L., Baeza-Lehnert, F., Chowdhry, S., Renden, R. B., Gonzalez-Aragón, G., Groschup, B., Hofmann, T., Jovanović, S., Sonntag, M., Gitler, D., Schaefer, M., Eilers, J., Barros, L. F., Hirrlinger, J. & Hallermann, S., 1 Sep 2025, In: Journal of Neurochemistry. 169, 9, e70212.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Structural and functional insights of ZnT1 C-terminal domain as a regulator of zinc transport
Ben Yosef, T. E., Kass, I., Shahar, A., Eremenko, E., Monsonego, A., Gitler, D., Moran, A. & Zarivach, R., 1 Dec 2025, In: Scientific Reports. 15, 1, 26920.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Synapsin E-domain is essential for α-synuclein function
Stavsky, A., Parra-Rivas, L. A., Tal, S., Riba, J., Madhivanan, K., Roy, S. & Gitler, D., 7 May 2024, In: eLife. 12Research output: Contribution to journal › Article › peer-review
Open Access -
Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
Bakavayev, S., Stavsky, A., Argueti-Ostrovsky, S., Yehezkel, G., Fridmann-Sirkis, Y., Barak, Z., Gitler, D., Israelson, A. & Engel, S., 1 Nov 2023, In: Brain. 146, 11, p. 4594-4607 14 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Frequency-and spike-timing-dependent mitochondrial Ca2+ signaling regulates the metabolic rate and synaptic efficacy in cortical neurons
Stoler, O., Stavsky, A., Khrapunsky, Y., Melamed, I., Stutzmann, G., Gitler, D., Sekler, I. & Fleidervish, I., 1 Feb 2022, In: eLife. 11, e74606.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation
Stavsky, A., Stoler, O., Kostic, M., Katoshevsky, T., Assali, E. A., Savic, I., Amitai, Y., Prokisch, H., Leiz, S., Daumer-Haas, C., Fleidervish, I., Perrochi, F., Gitler, D. & Sekler, I., 1 Dec 2021, In: Communications Biology. 4, 1, 666.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
BMP5/7 protect dopaminergic neurons in an α-synuclein mouse model of Parkinson's disease
Vitic, Z., Safory, H., Jovanovic, V. M., Sarusi, Y., Stavsky, A., Kahn, J., Kuzmina, A., Toker, L., Gitler, D., Taube, R., Friedel, R. H., Engelender, S. & Brodski, C., 1 Feb 2021, In: Brain. 144, 2, e15.Research output: Contribution to journal › Letter › peer-review
Open Access16 Scopus citations -
CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice
Halperin, D., Stavsky, A., Kadir, R., Drabkin, M., Wormser, O., Yogev, Y., Dolgin, V., Proskorovski-Ohayon, R., Perez, Y., Nudelman, H., Stoler, O., Rotblat, B., Lifschytz, T., Lotan, A., Meiri, G., Gitler, D. & Birk, O. S., 1 Dec 2021, In: Nature Communications. 12, 1, 6187.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations
Prizes
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Impact of alpha-synuclein on quantal synaptic transmission
Gitler, D. (PI)
1/10/24 → 30/09/28
Project: Research
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SYNDYS-ALS/FTD
De Vos, K. K. (PI), West, R. R. (CoPI), Collins, M. O. (CoPI), Livesey, M. M. (CoPI), Mead, R. J. R. J. (CoPI), Grierson, A. J. A. J. (CoPI), Henstridge, C. C. (CoPI) & Gitler, D. (CoPI)
30/09/24 → 29/09/29
Project: Research
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Regulation of presynaptic calcium dynamics, synaptic properties, and neuronal network activity by alpha-synuclein
Gitler, D. (PI)
1/10/22 → 30/09/27
Project: Research
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Reciprocal effects of alpha-synuclein on synaptic physiology
Gitler, D. (PI) & Roy, S. (CoPI)
United States-Israel Binational Science Foundation (BSF)
1/01/19 → …
Project: Research
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State-of-the-Art laboratory for Focused Ion Beam applications
Schvartzman, M. (PI), Gitler, D. (CoPI) & Sarusi, G. (CoPI)
1/01/16 → …
Project: Research
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Role of synapsin in alpha-synuclein-induced neurotoxicity
Gitler, D. (PI)
1/10/21 → 30/09/25
Project: Research
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Master regulators of synaptic vesicle clustering determine the structure and function of the presynaptic terminal
Gitler, D. (PI)
1/10/19 → 30/09/22
Project: Research
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Pathophysiologic roles of alpha-synuclein at the synapse
Roy, S. (PI) & Gitler, D. (CoPI)
15/08/19 → 31/05/21
Project: Research
Datasets
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Synapsin E-domain is essential for α-synuclein function, Imaging data
Gitler, D. (Creator), ZENODO, 25 Apr 2024
DOI: 10.5281/zenodo.11067289, https://zenodo.org11067289
Dataset