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Esti Yeger-Lotem

Professor, Ph.D.

 https://orcid.org/0000-0002-8279-7898
19972022

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Research interests

  • Bioninformatic
  • systems biology
  • network biology
  • tissue specificity
  • hereditary diseases

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  • The differential activity of biological processes in tissues and cell subsets can illuminate disease-related processes and cell type identities

    Sharon, M., Vinogradov, E., Argov, C. M., Lazarescu, O., Zoabi, Y., Hekselman, I. & Yeger-Lotem, E., 15 Mar 2022, In: Bioinformatics. 38, 6, p. 1584-1592 9 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • The Organ-Disease Annotations (ODiseA) Database of Hereditary Diseases and Inflicted Tissues

    Hekselman, I., Kerber, L., Ziv, M., Gruber, G. & Yeger-Lotem, E., 15 Jun 2022, In: Journal of Molecular Biology. 434, 11, 7 p., 167619.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • The TissueNet v.3 Database: Protein-protein Interactions in Adult and Embryonic Human Tissue contexts

    Ziv, M., Gruber, G., Sharon, M., Vinogradov, E. & Yeger-Lotem, E., 15 Jun 2022, In: Journal of Molecular Biology. 434, 11, 167532.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease

    GTEx Consortium, 13 May 2021, In: Cell. 184, 10, p. 2633-2648.e19

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

    Tiago, T., Hummel, B., Morelli, F. F., Basile, V., Vinet, J., Galli, V., Mediani, L., Antoniani, F., Pomella, S., Cassandri, M., Garone, M. G., Silvestri, B., Cimino, M., Cenacchi, G., Costa, R., Mouly, V., Poser, I., Yeger-Lotem, E., Rosa, A., Alberti, S., & 4 othersRota, R., Ben-Zvi, A., Sawarkar, R. & Carra, S., 1 May 2021, In: Cell Death and Disease. 12, 5, 452.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • The Landscape of Molecular Chaperones Across Human Tissues Reveals a Layered Architecture of Core and Variable Chaperones

    Shemesh, N., Jubran, J., Dror, S., Simonovsky, E., Basha, O., Argov, C., Hekselman, I., Abu-Qarn, M., Vinogradov, E., Mauer, O., Tiago, T., Carra, S., Ben-Zvi, A. & Yeger-Lotem, E., 12 Apr 2021, In: Nature Communications. 12, 1, 2180.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs

    Jayaram, D. R., Frost, S., Argov, C., Liju, V. B., Anto, N. P., Muraleedharan, A., Ben-Ari, A., Sinay, R., Smoly, I., Novoplansky, O., Isakov, N., Toiber, D., Keasar, C., Elkabets, M., Yeger-Lotem, E. & Livneh, E., 5 Oct 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 40, e2018899118.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • A Quantitative Proteome Map of the Human Body

    GTEx Consortium, 1 Oct 2020, In: Cell. 183, 1, p. 269-283.e19

    Research output: Contribution to journal › Article › peer-review

    Open Access
    97 Scopus citations

  • A reference map of the human binary protein interactome

    Luck, K., Kim, D. K., Lambourne, L., Spirohn, K., Begg, B. E., Bian, W., Brignall, R., Cafarelli, T., Campos-Laborie, F. J., Charloteaux, B., Choi, D., Coté, A. G., Daley, M., Deimling, S., Desbuleux, A., Dricot, A., Gebbia, M., Hardy, M. F., Kishore, N., Knapp, J. J., & 68 othersKovács, I. A., Lemmens, I., Mee, M. W., Mellor, J. C., Pollis, C., Pons, C., Richardson, A. D., Schlabach, S., Teeking, B., Yadav, A., Babor, M., Balcha, D., Basha, O., Bowman-Colin, C., Chin, S. F., Choi, S. G., Colabella, C., Coppin, G., D’Amata, C., De Ridder, D., De Rouck, S., Duran-Frigola, M., Ennajdaoui, H., Goebels, F., Goehring, L., Gopal, A., Haddad, G., Hatchi, E., Helmy, M., Jacob, Y., Kassa, Y., Landini, S., Li, R., van Lieshout, N., MacWilliams, A., Markey, D., Paulson, J. N., Rangarajan, S., Rasla, J., Rayhan, A., Rolland, T., San-Miguel, A., Shen, Y., Sheykhkarimli, D., Sheynkman, G. M., Simonovsky, E., Taşan, M., Tejeda, A., Tropepe, V., Twizere, J. C., Wang, Y., Weatheritt, R. J., Weile, J., Xia, Y., Yang, X., Yeger-Lotem, E., Zhong, Q., Aloy, P., Bader, G. D., De Las Rivas, J., Gaudet, S., Hao, T., Rak, J., Tavernier, J., Hill, D. E., Vidal, M., Roth, F. P. & Calderwood, M. A., 16 Apr 2020, In: Nature. 580, 7803, p. 402-408 7 p.

    Research output: Contribution to journal › Article › peer-review

    357 Scopus citations

  • A vast resource of allelic expression data spanning human tissues

    Castel, S. E., Aguet, F., Mohammadi, P., Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., Kashin, S., Li, X., MacArthur, D. G., Meier, S. R., Nedzel, J. L., Nguyen, D. T., Segrè, A. V., Todres, E., & 181 othersAguet, F., Anand, S., Ardlie, K. G., Balliu, B., Barbeira, A. N., Battle, A., Bonazzola, R., Brown, A., Brown, C. D., Castel, S. E., Conrad, D. F., Cotter, D. J., Cox, N., Das, S., De Goede, O. M., Dermitzakis, E. T., Einson, J., Engelhardt, B. E., Eskin, E., Eulalio, T. Y., Ferraro, N. M., Flynn, E. D., Fresard, L., Gamazon, E. R., Garrido-Martín, D., Gay, N. R., Gloudemans, M. J., Graubert, A., Guigó, R., Hadley, K., Hame, A. R., Handsaker, R. E., He, Y., Hoffman, P. J., Hormozdiari, F., Hou, L., Huang, K. H., Im, H. K., Jo, B., Kasela, S., Kashin, S., Kellis, M., Kim-Hellmuth, S., Kwong, A., Lappalainen, T., Li, X., Li, X., Liang, Y., Mangul, S., Meier, S. R., Mohammadi, P., Montgomery, S. B., Muñoz-Aguirre, M., Nachun, D. C., Nedzel, J. L., Nguyen, D. T., Nobel, A. B., Oliva, M., Park, Y. S., Park, Y., Parsana, P., Rao, A. S., Reverter, F., Rouhana, J. M., Sabatti, C., Saha, A., Segrè, A. V., Skol, A. D., Stephens, M., Stranger, B. E., Strober, B. J., Teran, N. A., Todres, E., Viñuela, A., Wang, G., Wen, X., Wright, F., Wucher, V., Zou, Y., Ferreira, P. G., Li, G., Melé, M., Yeger-Lotem, E., Barcus, M. E., Bradbury, D., Krubit, T., McLean, J. A., Qi, L., Robinson, K., Roche, N. V., Smith, A. M., Sobin, L., Tabor, D. E., Undale, A., Bridge, J., Brigham, L. E., Foster, B. A., Gillard, B. M., Hasz, R., Hunter, M., Johns, C., Johnson, M., Karasik, E., Kopen, G., Leinweber, W. F., McDonald, A., Moser, M. T., Myer, K., Ramsey, K. D., Roe, B., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Jewell, S. D., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Barcus, M. E., Branton, P. A., Sobin, L., Barker, L. K., Gardiner, H. M., Mosavel, M., Siminoff, L. A., Flicek, P., Haeussler, M., Juettemann, T., Kent, W. J., Lee, C. M., Powell, C. C., Rosenbloom, K. R., Ruffier, M., Sheppard, D., Taylor, K., Trevanion, S. J., Zerbino, D. R., Abell, N. S., Akey, J., Chen, L., Demanelis, K., Doherty, J. A., Feinberg, A. P., Hansen, K. D., Hickey, P. F., Hou, L., Jasmine, F., Jiang, L., Kaul, R., Kellis, M., Kibriya, M. G., Li, J. B., Li, Q., Lin, S., Linder, S. E., Montgomery, S. B., Oliva, M., Park, Y., Pierce, B. L., Rizzardi, L. F., Skol, A. D., Smith, K. S., Snyder, M., Stamatoyannopoulos, J., Stranger, B. E., Tang, H., Wang, M., Branton, P. A., Carithers, L. J., Guan, P., Koester, S. E., Little, A. R., Moore, H. M., Nierras, C. R., Rao, A. K., Vaught, J. B., Volpi, S., Ardlie, K. G. & Lappalainen, T., 11 Sep 2020, In: Genome Biology. 21, 1, 234.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations
View all 67 Research outputs
  • 2 Visiting an external academic institution