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1999 …2026

Research activity per year

Personal profile

Research interests

The main research effort in our lab is devoted to the design and synthesis of multi-component chemical systems, termed as Molecular Networks, and for analysis of their dynamic self-organization. This study within the new field of Systems Chemistry is inspired by the complexity in structure and function observed within cells.

Our findings can be used for understanding the organizational principles of biological systems, to shine light on plausible scenarios in early molecular evolution and the Origins of Life, and to develop devices of nanotechnology and biotechnology importance.

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Collaborations and top research areas from the last five years

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  • A Photo-Switchable Peptide Fibril Esterase

    Samanta, M., Saad, N., Wu, D., Crone, N. S. A., Abramov-Harpaz, K., Regev, C., Cohen-Luria, R., Boyle, A. L., Miller, Y., Kros, A. & Ashkenasy, G., 2 Jan 2025, In: Angewandte Chemie - International Edition. 64, 1, e202413810.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Bistable Functions and Signaling Motifs in Systems Chemistry: Taking the Next Step Toward Synthetic Cells

    Maity, I., Wagner, N., Dev, D. & Ashkenasy, G., 4 Feb 2025, In: Accounts of Chemical Research. 58, 3, p. 428-439 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Polymer–Carbon Black Composites for Humidity-Driven Water Uptake and Photothermally Induced Rapid Desorption

    Baranov, M., Ben Nun, U., Finestone, E. Y., Zhuravel, K., Shelonchik, O., Pavan, M., Shelly, L., Ashkenasy, G., Vainer, R. & Weizmann, Y., 13 Nov 2025, In: ACS Applied Materials and Interfaces. 17, 47, p. 64438-64450 13 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Engineering reaction networks by sequential signal processing

    Maity, I., Dev, D., Cohen-Luria, R., Wagner, N. & Ashkenasy, G., 11 Apr 2024, In: Chem. 10, 4, p. 1132-1146 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • A Peptide-Based Oscillator

    Dev, D., Wagner, N., Pramanik, B., Sharma, B., Maity, I., Cohen-Luria, R., Peacock-Lopez, E. & Ashkenasy, G., 6 Dec 2023, In: Journal of the American Chemical Society. 145, 48, p. 26279-26286 8 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Collectively autocatalytic sets

    Ashkenasy, G., Kauffman, S., Lancet, D., Otto, S., Ruiz-Mirazo, K., Semenov, S. & Xavier, J., 18 Oct 2023, In: Cell Reports Physical Science. 4, 10, 101594.

    Research output: Contribution to journalComment/debate

    Open Access
    5 Scopus citations
  • Dynamic exchange controls the assembly structure of nucleic-acid-peptide chimeras

    Sadihov-Hanoch, H., Bandela, A. K., Chotera-Ouda, A., Ben David, O., Cohen-Luria, R., Lynn, D. G. & Ashkenasy, G., 16 May 2023, In: Soft Matter. 19, 21, p. 3940-3945 6 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • The Systems Chemistry of Nucleic-acid-Peptide Networks

    Kumar Bandela, A., Sadihov-Hanoch, H., Cohen-Luria, R., Gordon, C., Blake, A., Poppitz, G., Lynn, D. G. & Ashkenasy, G., 1 Oct 2022, In: Israel Journal of Chemistry. 62, 9-10, e202200030.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    4 Scopus citations
  • Dynamic Surface Layer Coiled Coil Proteins Processing Analog-to-Digital Information

    Glionna, C., Kumar, V., Le Saux, G., Pramanik, B., Wagner, N., Cohen-Luria, R., Ashkenasy, G. & Ashkenasy, N., 27 Oct 2021, In: Journal of the American Chemical Society. 143, 42, p. 17441-17451 11 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Primitive selection of the fittest emerging through functional synergy in nucleopeptide networks

    Bandela, A. K., Wagner, N., Sadihov, H., Morales-Reina, S., Chotera-Ouda, A., Basu, K., Cohen-Luria, R., de la Escosura, A. & Ashkenasy, G., 2 Mar 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 9, e2015285118.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    38 Scopus citations