Research output per year
Research output per year
Professor of Nutrition & Epidemiology,
Research activity per year
endocrinology & metabolism
body fat composition
cardiometabolic risk
omics
microbiome
aging
epigenetics
polyphenols
weight Loss
diet
Iris Shai, RD, PhD, is a Professor of Nutrition and Epidemiology at BGU in the field of nutrition, aging and chronic diseases, Adjunct Professor at Harvard University & Honorary Professor in Leipzig University, Germany. Shai is the chair of the International center of Health Innovation& Nutrition, and a member in the Government Health Ministry Committee for healthy Nutrition Regulations in Israel. Her focuses are obesity, diabetes, aging, cognition, epigenetics, microubioum and cardiometabolic risk, while performing long-term, large scale, compressive dietary randomized controlled trials (RCTs) in standards of drugs trials, and long-term cohorts. Following her fellowship, awarded with Fulbright, in Harvard School of Public Health, where she focused on traditional and non-traditional biomarkers for CVD, she leaded, with her international research team, the 2-year Dietary Intervention Randomized Controlled Trial (DIRECT) and 4-year follow-up (A Dietary Intervention- Randomized Controlled Trial (DIRECT) Study), comparing the effects of dietary strategies on cardiometabolic risk and plaque regression. In her next trial , CASCADE (The CArdiovasCulAr Diabetes & Ethanol (CASCADE) Trial) she addressed the 2-year effect of moderate alcohol in type 2 diabetes and her recent whole-body MRI trial ,CENTRAL (Diet and Body Composition (CENTRAL)), focused on dynamic of human specific fat depots and fuel metabolism across dietary strategies. Recently, she completed the DIRECT PLUS trial (Effects of Green-MED Diet Via the Gut-fat-brain Axis (DIRECT-PLUS)), which explores the effect of green Med diet, high- polyphenols on the gut-fat-brain axis. In this trial new horizons were explored, related to Autologous Fecal Microbiota Transplantation, brain atrophy attenuation and epi-genetics. The above-mentioned clinical trials serve in global nutritional guidelines in the field of obesity, cardiology, diabetes and fatty liver diseases. Currently, Shai directs the FIT project (Follow Intervention Trials) project which aims to identify predictors & drivers determining personal health outcome, as age-related brain atrophy; as an integration of four long-term, large scale dietary clinical trials. The FIT will leverage huge omics data bank from various human specimen, MRI scans and health outcomes toward personal medicine approach.
Shai teaches and counselling in the areas of Novel Technologist in Dietary Clinical Trials and Effective Scientific Writing.
PhD, Ben-Gurion University of the Negev
1996 → 2002
Master, Hebrew University of Jerusalem
1993 → 1996
Adjunct Professor of Nutrition, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University
Honorary Professor , Leipzig University
Member in the Government Health Ministry Committee for healthy Nutrition Regulations in Israel and the Israeli Cardiology Association committee for nutritional guidelines for preventive cardiology , Ministry of Health, Israel
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Letter
Research output: Contribution to journal › Letter › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Iris Shai (Speaker) & Gal Tsaban (Speaker)
Activity: Talk or presentation › Invited talk
Iris Shai (Speaker)
Activity: Talk or presentation › Invited talk
Iris Shai (Other), Jack Gilron (Participant), Sagi (Participant), Sammy Boussiba (Participant), Aaron Fait (Participant) & Frank Hu (Other)
Activity: Other
Assaf Rudich (Other), Prof. Matthias Blüher (Participant), Amos Katz (Participant), Ilan Shelef (Participant), Iris Shai (Participant), Idit Liberty (Participant), Aya Biderman (Participant) & Dror Dicker (Participant)
Activity: Other
Iris Shai (Member)
Activity: Membership › Membership of council
Iris Shai (Member)
Activity: Membership › Membership of committee
Iris Shai (Participant)
Activity: Other
Shai, Iris (Recipient), 7 Nov 2019
Prize: Other distinction
Shai, Iris (Recipient), 1 Apr 2022
Prize: Honorary award
Shai, Iris (Recipient), 22 Jun 2021
Prize
Supervisor: Shai, I. (Supervisor)
Student thesis: Doctoral Thesis
Supervisor: Fraser, D. (Supervisor)
Student thesis: Doctoral Thesis
5/06/21
1 Media contribution
Press/Media
21/03/22
1 Media contribution
Press/Media
1/07/22
1 Media contribution
Press/Media
24/03/22
1 Media contribution
Press/Media
Shai, I. & Youngster, I.
Israel Science Foundation (ISF)
1/01/18 → 31/12/21
Project: Research
Sherwood, C. C., Durst, R., Sacks, F., Stampfer, M., Durst, R., Schwarzfuchs, D. & Shai, I.
United States-Israel Binational Science Foundation (BSF)
1/01/11 → 31/12/16
Project: Research
Rinott, E. (Creator), Meir, A. Y. (Creator), Tsaban, G. (Creator), Zelicha Peer, H. (Creator), Kaplan, A. (Creator), Knights, D. (Creator), Tuohy, K. (Creator), Scholz, M. U. (Creator), Koren, O. (Creator), Stampfer, M. J. (Creator), Wang, D. D. (Creator), Shai, I. (Owner) & Youngster, I. (Creator), figshare, 10 Mar 2022
DOI: 10.6084/m9.figshare.c.5886834.v1, https://springernature.figshare.com/collections/The_effects_of_the_Green-Mediterranean_diet_on_cardiometabolic_health_are_linked_to_gut_microbiome_modifications_a_randomized_controlled_trial/5886834/1
Dataset
Wang, M. (Creator), Xue, Q. (Creator), Li, X. (Creator), Krohn, K. (Creator), Ziesche, S. (Creator), Ceglarek, U. (Creator), Blüher, M. (Creator), Keller, M. (Creator), Meir, A. Y. (Creator), Heianza, Y. (Creator), Kovacs, P. (Creator), Shai, I. (Creator) & Qi, L. (Creator), figshare, 10 Dec 2021
DOI: 10.6084/m9.figshare.17156342.v1, https://figshare.com/articles/figure/Supplementary_information_for_Circulating_levels_of_microRNA-122_and_hepatic_fat_change_in_response_to_weight-loss_interventions_CENTRAL_Trial/17156342/1
Dataset
Meir, A. Y. (Creator), Keller, M. (Creator), Bernhart, S. H. (Creator), Rinott, E. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Kaplan, A. (Creator), Schwarzfuchs, D. (Creator), Shelef, I. (Creator), Gepner, Y. (Creator), Li, J. (Creator), Lin, Y. (Creator), Blüher, M. (Creator), Ceglarek, U. (Creator), Stumvoll, M. (Creator), Stadler, P. F. (Creator), Stampfer, M. J. (Creator), Kovacs, P. (Creator), Liang, L. (Creator) & Shai, I. (Creator), figshare, 3 May 2021
DOI: 10.6084/m9.figshare.c.5328052.v1, https://springernature.figshare.com/collections/Lifestyle_weight-loss_intervention_may_attenuate_methylation_aging_the_CENTRAL_MRI_randomized_controlled_trial/5328052/1
Dataset
Levakov, G. (Creator), Kaplan, A. (Creator), Meir, A. Y. (Creator), Rinott, E. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Meiran, N. (Creator), Shelef, I. (Creator), Shai, I. (Supervisor) & Avidan, G. (Supervisor), figshare, 27 Jun 2019
DOI: 10.6084/m9.figshare.c.4557347.v1, https://figshare.com/collections/Neural_correlates_of_future_weight_loss/4557347/1
Dataset