Research output per year
Research output per year
Professor of Nutrition & Epidemiology,
Research activity per year
Shai Iris, RD, Ph.D., is a Professor of Nutrition and Epidemiology at BGU in nutrition, aging, and chronic diseases, an Adjunct Professor at Harvard University & Honorary Professor at Leipzig University, Germany. Shai is the Chair of the International Center of Health Innovation& Nutrition, Chair of the Cathedra of Epidemiology named by Dr. Herman Kessel, former BGU President's deputy on the advancement of women in academia, and a member of the Government Health Ministry Committee for Healthy Nutrition Regulations in Israel. Her focuses are obesity, diabetes, aging, cognition, epigenetics, microbiome, and cardiometabolic risk while performing long-term, large-scale compressive dietary randomized controlled trials (RCTs) in standards of drugs trials and long-term cohorts. Following her fellowship, awarded with Fulbright, in Harvard School of Public Health, where she focused on traditional and non-traditional biomarkers for CVD, she led, with her international research team, the 2-year Dietary Intervention Randomized Controlled Trial (DIRECT) and 4-year follow-up (A Dietary Intervention- Randomized Controlled Trial (DIRECT) Study), comparing the effects of dietary strategies on cardiometabolic risk and plaque regression. In her next trial, CASCADE (The CArdiovasCulAr Diabetes & Ethanol (CASCADE) Trial), she addressed the 2-year effect of moderate alcohol in type 2 diabetes and her recent whole-body MRI trial, CENTRAL (Diet and Body Composition (CENTRAL)), focused on dynamic of human-specific fat depots and fuel metabolism across dietary strategies. Recently, she completed the DIRECT PLUS trial (Effects of Green-MED Diet Via the Gut-fat-brain Axis (DIRECT-PLUS)), which explores the effect of green Med diet and high- polyphenols on the gut-fat-brain axis. In this trial, new horizons were explored related to Autologous Fecal Microbiota Transplantation, brain atrophy attenuation, and epigenetics. The above-mentioned clinical trials serve in global nutritional guidelines in obesity, cardiology, diabetes, and fatty liver diseases. Currently, Shai directs the Follow Intervention Trials (FIT) project, which aims to identify predictors & drivers determining personal health outcomes, such as age-related brain atrophy, utilizing an AI integration of four long-term, large-scale dietary clinical trials. The FIT will leverage a vast omics data bank from various human specimens, MRI scans, and health outcomes towards an approach of personalized medicine for overall health and specific clinical outcome. As part of Prof. Shai’s FIT project, data from the past four RCTs will be integrated for ~1000 participants with ~2000 person-years of intervention, with 5–16-year follow-up measures. MRI and clinical and biological samples will be measured, including biomarkers from blood, feces, urine, hair, nails, and saliva.
Shai teaches and counsels in the areas of Novel Technologists in Dietary Clinical Trials and Effective Scientific Writing.
Key publications: Current H-index = 57 (i10-index = 110); Total citations = 15,555
PhD, Ben-Gurion University of the Negev
1996 → 2002
Master, Hebrew University of Jerusalem
1993 → 1996
Adjunct Professor of Nutrition, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University
Honorary Professor , Leipzig University
Member in the Government Health Ministry Committee for healthy Nutrition Regulations in Israel and the Israeli Cardiology Association committee for nutritional guidelines for preventive cardiology , Ministry of Health, Israel
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Letter
Research output: Contribution to journal › Letter › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Iris Shai (Speaker) & Gal Tsaban (Speaker)
Activity: Talk or presentation › Invited talk
Iris Shai (Speaker)
Activity: Talk or presentation › Invited talk
Iris Shai (Visiting researcher)
Activity: Visiting an external institution › Visiting an external academic institution
Iris Shai (Visiting researcher)
Activity: Visiting an external institution › Visiting an external academic institution
Iris Shai (Speaker)
Activity: Talk or presentation › Invited talk
Iris Shai (Other), Jack Gilron (Participant), Sagi (Participant), Sammy Boussiba (Participant), Aaron Fait (Participant) & Frank Hu (Other)
Activity: Other
Assaf Rudich (Other), Prof. Matthias Blüher (Participant), Amos Katz (Participant), Ilan Shelef (Participant), Iris Shai (Participant), Idit Liberty (Participant), Aya Biderman (Participant) & Dror Dicker (Participant)
Activity: Other
Iris Shai (Member)
Activity: Membership › Membership of council
Iris Shai (Member)
Activity: Membership › Membership of committee
Shai, Iris (Recipient), 7 Nov 2019
Prize: Other distinction
Shai, Iris (Recipient), 1 Apr 2022
Prize: Honorary award
Shai, Iris (Recipient), 2 Apr 2022
Prize: Honorary award
Shai, Iris (Recipient), 22 Jun 2021
Prize
5/06/21
1 Media contribution
Press/Media
21/03/22
1 Media contribution
Press/Media
Iris Shai & Gal Tsaban
17/05/23
1 Media contribution
Press/Media
Iris Shai & Gal Tsaban
14/05/23
1 item of Media coverage
Press/Media
Iris Shai & Gal Tsaban
11/05/23
1 Media contribution
Press/Media
28/11/22
1 item of Media coverage
Press/Media
Shai, I., Shelef, I. & Brickner, D.
1/01/17 → 31/03/19
Project: Other
Shai, I., Shelef, I. & Tsaban, G.
1/12/16 → 28/02/17
Project: Other
Shai, I., Schwarzfuchs, D. & Shelef, I.
1/10/12 → 30/04/14
Project: Other
Shai, I. & Henkin, Y.
1/06/10 → 31/05/12
Project: Research
Shai, I., Shelef, I. & Schwarzfuchs, D.
1/07/05 → 31/07/07
Project: Other
Shai, I. (Owner), Zelicha Peer, H. (Creator), Kloting, N. (Other), Kaplan, A. (Creator), Yaskolka Meir, A. (Creator), Rinott, E. (Creator), Tsaban, G. (Creator), Chassidim, Y. (Data Collector), Bluher, M. (Other), Ceglarek, U. (Other), Isermann, B. (Other), Stumvoll, M. (Other), Quayson, R. N. (Creator), von Bergen, M. (Creator), Engelmann, B. (Other), Rolle-Kampczyk, U. E. (Other), Haange, S. (Other), Tuohy, K. M. (Other), Diotallevi, C. (Other), Shelef, I. (Other), Hu, F. B. (Other) & Stampfer, M. J. (Contributor), figshare, 30 Sep 2022
DOI: 10.6084/m9.figshare.c.6225338.v1, https://springernature.figshare.com/collections/The_effect_of_high-polyphenol_Mediterranean_diet_on_visceral_adiposity_the_DIRECT_PLUS_randomized_controlled_trial/6225338/1
Dataset
Keller, M. (Creator), Meir, A. Y. (Creator), Bernhart, S. H. (Creator), Gepner, Y. (Creator), Shelef, I. (Creator), Schwarzfuchs, D. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Hopp, L. (Creator), Müller, L. (Creator), Rohde, K. (Creator), Böttcher, Y. (Creator), Stadler, P. F. (Creator), Stumvoll, M. (Creator), Blüher, M. (Creator), Kovacs, P. (Creator) & Shai, I. (Creator), figshare, 17 Nov 2020
DOI: 10.6084/m9.figshare.c.5209634.v1, https://springernature.figshare.com/collections/DNA_methylation_signature_in_blood_mirrors_successful_weight-loss_during_lifestyle_interventions_the_CENTRAL_trial/5209634/1
Dataset
Tsaban, G. (Creator), Yaskolka Meir, A. (Creator), Zelicha, H. (Creator), Rinott, E. (Creator), Kaplan, A. (Creator), Shalev, A. (Creator), Katz, A. (Creator), Brikner, D. (Creator), Blüher, M. (Creator), Ceglarek, U. (Creator), Stumvoll, M. (Creator), Stampfer, M. J. (Creator) & Shai, I. (Owner), ZENODO, 19 Jun 2021
DOI: 10.5281/zenodo.5115101, https://zenodo.org/record/5115101
Dataset
Wang, M. (Creator), Xue, Q. (Creator), Li, X. (Creator), Krohn, K. (Creator), Ziesche, S. (Creator), Ceglarek, U. (Creator), Blüher, M. (Creator), Keller, M. (Creator), Meir, A. Y. (Creator), Heianza, Y. (Creator), Kovacs, P. (Creator), Shai, I. (Creator) & Qi, L. (Creator), figshare, 12 Jan 2022
DOI: 10.6084/m9.figshare.17156342.v2, https://figshare.com/articles/figure/Supplementary_information_for_Circulating_levels_of_microRNA-122_and_hepatic_fat_change_in_response_to_weight-loss_interventions_CENTRAL_Trial/17156342/2
Dataset
Meir, A. Y. (Creator), Keller, M. (Creator), Bernhart, S. H. (Creator), Rinott, E. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Kaplan, A. (Creator), Schwarzfuchs, D. (Creator), Shelef, I. (Creator), Gepner, Y. (Creator), Li, J. (Creator), Lin, Y. (Creator), Blüher, M. (Creator), Ceglarek, U. (Creator), Stumvoll, M. (Creator), Stadler, P. F. (Creator), Stampfer, M. J. (Creator), Kovacs, P. (Creator), Liang, L. (Creator) & Shai, I. (Creator), figshare, 3 May 2021
DOI: 10.6084/m9.figshare.c.5328052.v1, https://springernature.figshare.com/collections/Lifestyle_weight-loss_intervention_may_attenuate_methylation_aging_the_CENTRAL_MRI_randomized_controlled_trial/5328052/1
Dataset
Keller, M. (Creator), Meir, A. Y. (Creator), Bernhart, S. H. (Creator), Gepner, Y. (Creator), Shelef, I. (Creator), Schwarzfuchs, D. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Hopp, L. (Creator), Müller, L. (Creator), Rohde, K. (Creator), Böttcher, Y. (Creator), Stadler, P. F. (Creator), Stumvoll, M. (Creator), Blüher, M. (Creator), Kovacs, P. (Creator) & Shai, I. (Creator), figshare, 17 Nov 2020
DOI: 10.6084/m9.figshare.13245863.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_DNA_methylation_signature_in_blood_mirrors_successful_weight-loss_during_lifestyle_interventions_the_CENTRAL_trial/13245863/1
Dataset
Rinott, E. (Creator), Meir, A. Y. (Creator), Tsaban, G. (Creator), Zelicha Peer, H. (Creator), Kaplan, A. (Creator), Knights, D. (Creator), Tuohy, K. (Creator), Scholz, M. U. (Creator), Koren, O. (Creator), Stampfer, M. J. (Creator), Wang, D. D. (Creator), Shai, I. (Owner) & Youngster, I. (Creator), figshare, 10 Mar 2022
DOI: 10.6084/m9.figshare.c.5886834.v1, https://springernature.figshare.com/collections/The_effects_of_the_Green-Mediterranean_diet_on_cardiometabolic_health_are_linked_to_gut_microbiome_modifications_a_randomized_controlled_trial/5886834/1
Dataset
Wang, M. (Creator), Xue, Q. (Creator), Li, X. (Creator), Krohn, K. (Creator), Ziesche, S. (Creator), Ceglarek, U. (Creator), Blüher, M. (Creator), Keller, M. (Creator), Meir, A. Y. (Creator), Heianza, Y. (Creator), Kovacs, P. (Creator), Shai, I. (Creator) & Qi, L. (Creator), figshare, 10 Dec 2021
DOI: 10.6084/m9.figshare.17156342.v1, https://figshare.com/articles/figure/Supplementary_information_for_Circulating_levels_of_microRNA-122_and_hepatic_fat_change_in_response_to_weight-loss_interventions_CENTRAL_Trial/17156342/1
Dataset
Levakov, G. (Creator), Kaplan, A. (Creator), Meir, A. Y. (Creator), Rinott, E. (Creator), Tsaban, G. (Creator), Zelicha, H. (Creator), Meiran, N. (Creator), Shelef, I. (Creator), Shai, I. (Supervisor) & Avidan, G. (Supervisor), figshare, 27 Jun 2019
DOI: 10.6084/m9.figshare.c.4557347.v1, https://figshare.com/collections/Neural_correlates_of_future_weight_loss/4557347/1
Dataset