Research output per year
Research output per year
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Dive into the research topics where Israel Sekler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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The role of the SLC25A15 transporter in the formation of liver metastasis in ESR1-mutated breast cancer
Taya, M., Fishman, D., Kanani, F., Zinger, L., Merenbakh-Lamin, K., Elfasi Sosner, S., Shendge, A. K., Klein Goldberg, A., Wolf, U., Winkler, G., Shifrut, E., Cohen, S., Wolf, I., Sekler, I. & Rubinek, T., 1 Jan 2026, (Accepted/In press) In: Oncogene.Research output: Contribution to journal › Article › peer-review
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Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer’s disease patients
Mustaly-Kalimi, S., Gallegos, W., Steinbrenner, D., Gupta, S., Houcek, A. J., Bennett, D. A., Marr, R. A., Peterson, D. A., Sekler, I. & Stutzmann, G. E., 1 Dec 2025, In: Acta Neuropathologica Communications. 13, 1, 165.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The zinc receptor, ZnR/GPR39, modulates taste sensitivity by regulating ion secretion in mouse salivary gland
Melamed, M., Asraf, H., Livne, N., Bogdanovic, M., Shendge, A., Shamir, G., Mero, M., Adir, O., Schroeder, A., Sekler, I. & Hershfinkel, M., 21 Feb 2025, In: iScience. 28, 2, 111912.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala
Sagi, R., Chakraborty, M., Bogdanovic, M., Asraf, H., Sekler, I., Kofman, O., Cohen, H. & Hershfinkel, M., 1 Dec 2024, In: Behavioral and Brain Functions. 20, 1, 31.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
NCLX controls hepatic mitochondrial Ca2+ extrusion and couples hormone-mediated mitochondrial Ca2+ oscillations with gluconeogenesis
Taha, M., Assali, E. A., Ben-Kasus Nissim, T., Stutzmann, G. E., Shirihai, O. S., Hershfinkel, M. & Sekler, I., 1 Sep 2024, In: Molecular Metabolism. 87, 101982.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
ZnR/GPR39 regulates hepatic insulin signaling, tunes liver bioenergetics and ROS production, and mitigates liver fibrosis and injury
Shendge, A. K., Sekler, I. & Hershfinkel, M., 1 Dec 2024, In: Redox Biology. 78, 103403.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery
Novorolsky, R. J., Kasheke, G. D. S., Hakim, A., Foldvari, M., Dorighello, G. G., Sekler, I., Vuligonda, V., Sanders, M. E., Renden, R. B., Wilson, J. J. & Robertson, G. S., 1 Jan 2023, In: Frontiers in Cellular Neuroscience. 17, 1226630.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
ASIC1a senses lactate uptake to regulate metabolism in neurons
Azoulay, I. S., Qi, X., Rozenfeld, M., Liu, F., Hu, Q., Ben Kasus Nissim, T., Stavsky, A., Zhu, M. X., Xu, T. L. & Sekler, I., 1 May 2022, In: Redox Biology. 51, 102253.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca2+ via Mitochondrial NCLX
Katoshevski, T., Bar, L., Tikochinsky, E., Harel, S., Ben-Kasus Nissim, T., Bogeski, I., Hershfinkel, M., Attali, B. & Sekler, I., 1 Dec 2022, In: Cells. 11, 24, 3990.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
Hagenston, A. M., Yan, J., Bas-Orth, C., Tan, Y., Sekler, I. & Bading, H., 1 Feb 2022, In: Journal of Biological Chemistry. 298, 2, 101508.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations
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A Seahorse system for monitoring metabolic activity in cell and tissues.
Sekler, I. (PI)
1/01/21 → …
Project: Research
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Multiphoton system for in-vivo and in-vitro imaging ofbrain, tissues and cells
Fleidervish, I. (PI), Sekler, I. (CoPI) & Monsonego, A. (CoPI)
1/01/15 → …
Project: Research
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Multiphoton system for in-vivo and in-vitro imaging of brain, tissues and cells
Fleidervish, I. (PI), Sekler, I. (CoPI) & Monsonego, A. (CoPI)
1/01/15 → …
Project: Research
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The role of zinc ions in biology: cellular mechanisms, physiological importance and clinical implication.
Hershfinkel, M. (PI), Silverman, Z. (CoPI) & Sekler, I. (CoPI)
1/01/09 → …
Project: Research
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Intracellular organelle deficits driving Alzheimer's disease
Stutzmann, G. (PI) & Sekler, I. (CoPI)
1/09/24 → 31/08/25
Project: Research
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Physiological implication of mitochondrial Na+/Ca2+ exchanger, NCLX, regulation by the PKA pathway
Sekler, I. (PI)
1/01/21 → 31/12/25
Project: Research
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Physiological implications of mitochondrial Na+/Ca2+ exchanger (NCLX) regulation by membrane potential and phosphorylation
Sekler, I. (PI)
1/01/17 → 31/12/20
Project: Research
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Physiological implications of mitochondrial Na+/Ca2+ exchanger (NCLX) regulation by membrane potential and phosphorylation
Sekler, I. (PI)
1/01/17 → 31/12/20
Project: Research
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Multiphoton system for in-vivo and in-vitro imaging of brain, tissues and cells
Fleidervish, I. (PI), Sekler, I. (CoPI) & Monsonego, A. (CoPI)
1/01/15 → 31/12/15
Project: Research