Personal profile
Research interests
Biophysics and Cellular Biomechanics. Jamming and Unjamming transitions in epithelial cells. Mechanical inhibition of cellular proliferation.
We experimentally study multicellular mechanical features of epithelial cells, as they relate to collective cellular migration, wound healing, and cancer invasion.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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ConfluentFUCCI for fully-automated analysis of cell-cycle progression in a highly dense collective of migrating cells
Goldstien, L., Lavi, Y. & Atia, L., 1 Jun 2024, In: PLOS ONE. 19, 6 June, e0305491.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A life off the beaten track in biomechanics: Imperfect elasticity, cytoskeletal glassiness, and epithelial unjamming
Atia, L. & Fredberg, J. J., 1 Dec 2023, In: Biophysics Reviews. 4, 4, 041304.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Are cell jamming and unjamming essential in tissue development?
Atia, L., Fredberg, J. J., Gov, N. S. & Pegoraro, A. F., 1 Dec 2021, In: Cells and Development. 168, 203727.Research output: Contribution to journal › Review article › peer-review
Open Access61 Scopus citations -
Unjamming and collective migration in MCF10A breast cancer cell lines
Kim, J. H., Pegoraro, A. F., Das, A., Koehler, S. A., Ujwary, S. A., Lan, B., Mitchel, J. A., Atia, L., He, S., Wang, K., Bi, D., Zaman, M. H., Park, J. A., Butler, J. P., Lee, K. H., Starr, J. R. & Fredberg, J. J., 15 Jan 2020, In: Biochemical and Biophysical Research Communications. 521, 3, p. 706-715 10 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
The tumor suppressor p53 can promote collective cellular migration
He, S., Carman, C. V., Lee, J. H., Lan, B., Koehler, S., Atia, L., Park, C. Y., Kim, J. H., Mitchel, J. A., Park, J. A., Butler, J. P., Lu, Q. & Fredberg, J. J., 1 Feb 2019, In: PLOS ONE. 14, 2, e0202065.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Contact guidance and collective migration in the advancing epithelial monolayer
Lee, G., Atia, L., Lan, B., Sharma, Y., Nissim, L., Wu, M. R., Pery, E., Lu, T. K., Park, C. Y., Butler, J. P. & Fredberg, J. J., 4 Jul 2018, In: Connective Tissue Research. 59, 4, p. 309-315 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Geometric constraints during epithelial jamming
Atia, L., Bi, D., Sharma, Y., Mitchel, J. A., Gweon, B., Koehler, S. A., Decamp, S. J., Lan, B., Kim, J. H., Hirsch, R., Pegoraro, A. F., Lee, K. H., Starr, J. R., Weitz, D. A., Martin, A. C., Park, J. A., Butler, J. P. & Fredberg, J. J., 1 Jun 2018, In: Nature Physics. 14, 6, p. 613-620 8 p.Research output: Contribution to journal › Article › peer-review
Open Access206 Scopus citations -
Publisher Correction: Geometric constraints during epithelial jamming(Nature Physics (2018) DOI: 10.1038/s41567-018-0089-9)
Atia, L., Bi, D., Sharma, Y., Mitchel, J. A., Gweon, B., Koehler, S. A., Decamp, S. J., Lan, B., Kim, J. H., Hirsch, R., Pegoraro, A. F., Lee, K. H., Starr, J. R., Weitz, D. A., Martin, A. C., Park, J. A., Butler, J. P. & Fredberg, J. J., 1 Jun 2018, In: Nature Physics. 14, 6, p. 629 1 p.Research output: Contribution to journal › Comment/debate
Open Access5 Scopus citations -
Publisher Correction: Geometric constraints during epithelial jamming (Nature Physics (2018) DOI: 10.1038/s41567-018-0089-9)
Atia, L., Bi, D., Sharma, Y., Mitchel, J. A., Gweon, B., Koehler, S. A., Decamp, S. J., Lan, B., Kim, J. H., Hirsch, R., Pegoraro, A. F., Lee, K. H., Starr, J. R., Weitz, D. A., Martin, A. C., Park, J. A., Butler, J. P. & Fredberg, J. J., 1 Jun 2018, In: Nature Physics. 14, 6, p. 629 1 p.Research output: Contribution to journal › Comment/debate
Open Access2 Scopus citations -
Scaling physiologic function from cell to tissue in asthma, cancer, and development
Sharma, Y., Atia, L., Rhodes, C. S., DeCamp, S. J., Mitchel, J. & Fredberg, J. J., 1 Feb 2018, In: Annals of the American Thoracic Society. 15, p. S35-S37Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
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The role of cellular jamming in mechanical inhibition of cell division
Atia, L. (PI)
1/01/21 → 31/12/24
Project: Research