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Liron David

 https://orcid.org/0000-0002-9750-543X
20132024

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  • NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks

    David, L., Borges, J. P., Hollingsworth, L. R., Volchuk, A., Jansen, I., Garlick, E., Steinberg, B. E. & Wu, H., 25 Apr 2024, In: Cell. 187, 9, p. 2224-2235.e16

    Research output: Contribution to journal › Article › peer-review

    Open Access
    98 Scopus citations

  • ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

    Du, G., Healy, L. B., David, L., Walker, C., El-Baba, T. J., Lutomski, C. A., Goh, B., Gu, B., Pi, X., Devant, P., Fontana, P., Dong, Y., Ma, X., Miao, R., Balasubramanian, A., Puthenveetil, R., Banerjee, A., Luo, H. R., Kagan, J. C. & Oh, S. F. & 3 others, Robinson, C. V., Lieberman, J. & Wu, H., 13 Jun 2024, In: Nature. 630, 8016, p. 437-446 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    200 Scopus citations

  • Piezo mechanosensory channels regulate centrosome integrity and mitotic entry

    David, L., Martinez, L., Xi, Q., Kooshesh, K. A., Zhang, Y., Shah, J. V., Maas, R. L. & Wu, H., 3 Jan 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 1, e2213846120.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL

    Xia, M., David, L., Teater, M., Gutierrez, J., Wang, X., Meydan, C., Lytle, A., Slack, G. W., Scott, D. W., Morin, R. D., Onder, O., Elenitoba-Johnson, K. S. J., Zamponi, N., Cerchietti, L., Lu, T., Philippar, U., Fontan, L., Wu, H. & Melnick, A. M., 1 Aug 2022, In: Cancer Discovery. 12, 8, p. 1922-1941 20 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations

  • Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes

    Robert Hollingsworth, L., David, L., Li, Y., Griswold, A. R., Ruan, J., Sharif, H., Fontana, P., Orth-He, E. L., Fu, T. M., Bachovchin, D. A. & Wu, H., 1 Dec 2021, In: Nature Communications. 12, 1, 189.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    69 Scopus citations

  • NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation

    Andreeva, L., David, L., Rawson, S., Shen, C., Pasricha, T., Pelegrin, P. & Wu, H., 22 Dec 2021, In: Cell. 184, 26, p. 6299-6312.e22

    Research output: Contribution to journal › Article › peer-review

    Open Access
    219 Scopus citations

  • Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly

    Stinson, J. R., Dorjbal, B., McDaniel, D. P., David, L., Wu, H. & Snow, A. L., 1 Jul 2020, In: Cellular Immunology. 353, 104129.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization

    Hauseman, Z. J., Harvey, E. P., Newman, C. E., Wales, T. E., Bucci, J. C., Mintseris, J., Schweppe, D. K., David, L., Fan, L., Cohen, D. T., Herce, H. D., Mourtada, R., Ben-Nun, Y., Bloch, N. B., Hansen, S. B., Wu, H., Gygi, S. P., Engen, J. R. & Walensky, L. D., 2 Jul 2020, In: Molecular Cell. 79, 1, p. 68-83.e7

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Assembly mechanism of the CARMA1–BCL10–MALT1–TRAF6 signalosome

    David, L., Li, Y., Ma, J., Garner, E., Zhang, X. & Wu, H., 13 Feb 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. 1499-1504 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    91 Scopus citations

  • Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

    Zhang, L., Chen, S., Ruan, J., Wu, J., Tong, A. B., Yin, Q., Li, Y., David, L., Lu, A., Wang, W. L., Marks, C., Ouyang, Q., Zhang, X., Mao, Y. & Wu, H., 23 Oct 2015, In: Science. 350, 6259, p. 404-409 6 p.

    Research output: Contribution to journal › Article › peer-review

    339 Scopus citations
View all 12 Research outputs