Research output per year
Research output per year
Personal profile
Research interests
The research I lead is focused on two main directions that branch into several exciting and novel drug development projects: Bioorganic & Medicinal Chemistry and Pharmacology. The field of Bioorganic and Medicinal Chemistry combines design and synthesis (structure-activity relationship), drug delivery approaches (pro-drugs), targeting and mechanistic studies, and bio-analytical studies. The work centers on interrelationships between chemistry and biological activities, including the evaluation of different disease models. The field of pharmacology combines ‘anti-cancer and anti-inflammatory studies’, pharmacological evaluation of biomedically important bioactive compounds, towards drug discovery, including collaboration with AI and machine learning team.
Fingerprint
Dive into the research topics where Shimon Ben-Shabat is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Antimicrobial and Antiviral Compounds of Phlomis viscosa Poiret
Yarmolinsky, L., Nakonechny, F., Budovsky, A., Zeigerman, H., Khalfin, B., Sharon, E., Yarmolinsky, L., Ben-Shabat, S. & Nisnevitch, M., 1 Feb 2023, In: Biomedicines. 11, 2, 441.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cannabidiol-Loaded Lipid-Stabilized Nanoparticles Alleviate Psoriasis Severity in Mice: A New Approach for Improved Topical Drug Delivery
Zamansky, M., Yariv, D., Feinshtein, V., Ben-Shabat, S. & Sintov, A. C., 1 Oct 2023, In: Molecules. 28, 19, 6907.Research output: Contribution to journal › Article › peer-review
Open Access -
Cannabidiol-Loaded Nanoparticles Based on Crosslinked Starch: Anti-Inflammatory Activity and Improved Nose-to-Brain Delivery
Eydelman, I., Zehavi, N., Feinshtein, V., Kumar, D., Ben-Shabat, S. & Sintov, A. C., 23 Jun 2023, In: Pharmaceutics. 15, 7, 1803.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Fundamental Role of Lipids in Polymeric Nanoparticles: Dermal Delivery and Anti-Inflammatory Activity of Cannabidiol
Zamansky, M., Zehavi, N., Sintov, A. C. & Ben-Shabat, S., 1 Feb 2023, In: Molecules. 28, 4, 1774.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Therapeutic Potential of Phytocannabinoid Cannabigerol for Multiple Sclerosis: Modulation of Microglial Activation In Vitro and In Vivo
Fleisher-Berkovich, S., Ventura, Y., Amoyal, M., Dahan, A., Feinshtein, V., Alfahel, L., Israelson, A., Bernstein, N., Gorelick, J. & Ben-Shabat, S., 1 Feb 2023, In: Biomolecules. 13, 2, 376.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Editorial: Medicinal Cannabis: Evolution of therapeutic use, future approaches and other implications
Brusa, P., Baratta, F., Collino, M. & Ben -Shabat, S., 25 Aug 2022, In: Frontiers in Pharmacology. 13, 999068.Research output: Contribution to journal › Editorial
Open Access2 Scopus citations -
Medicinal Properties of Anchusa strigosa and Its Active Compounds
Yarmolinsky, L., Budovsky, A., Khalfin, B., Yarmolinsky, L. & Ben-Shabat, S., 1 Dec 2022, In: Molecules. 27, 23, 8239.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
PLA2-Triggered Activation of Cyclosporine-Phospholipid Prodrug as a Drug Targeting Approach in Inflammatory Bowel Disease Therapy
Markovic, M., Ben-Shabat, S., Manda, J. N., Abramov-Harpaz, K., Regev, C., Miller, Y., Aponick, A., Zimmermann, E. M. & Dahan, A., 18 Mar 2022, In: Pharmaceutics. 14, 3, 12 p., 675.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Prodrug-Based Targeting Approach for Inflammatory Bowel Diseases Therapy: Mechanistic Study of Phospholipid-Linker-Cyclosporine PLA2-Mediated Activation
Markovic, M., Abramov-Harpaz, K., Regev, C., Ben-Shabat, S., Aponick, A., Zimmermann, E. M., Miller, Y. & Dahan, A., 1 Mar 2022, In: International Journal of Molecular Sciences. 23, 5, 2673.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Targeted Prodrugs in Oral Drug Delivery
Markovic, M., Ben-Shabat, S. & Dahan, A., 1 Jan 2022, Targeted Drug Delivery. wiley, p. 169-192 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review