Keyphrases
Escherichia Coli
100%
Methylenetetrahydrofolate Reductase (MTHFR)
91%
Mutation Effect
59%
Fitness Landscape
54%
S-adenosylmethionine Decarboxylase
41%
TEM-1
36%
Drug Resistance
34%
Fitness Effects
30%
Horizontal Gene Transfer
28%
Lineage Diversity
27%
Point mutation
27%
Gene Dosage
27%
Overexpression
26%
Epistasis
25%
Evolutionary Dynamics
25%
Trimethoprim
25%
Metabolic Enzymes
24%
S-adenosylmethionine
23%
Trimethoprim Resistance
22%
Destabilizing mutations
22%
Deleterious mutations
20%
System Level
20%
Laboratory Evolution
20%
Antibiotics
20%
Functional Integration
18%
Horizontally Transferred Genes
18%
Protein Abundance
18%
Evolutionary Fate
18%
Evolvable
18%
Neutral Drift
18%
Mutational Drift
18%
Protein Quality Control
18%
Antibiotic Levels
18%
Adaptation
18%
Molecular Properties
17%
Orthologs
17%
Purging
17%
FolA
16%
Tricarboxylic Acid Cycle (TCA cycle)
16%
Genotype-phenotype Association
16%
Protein Homeostasis
16%
High-throughput
16%
Methionine
15%
Homotetramer
14%
Evolutionary Implications
14%
Evolutionary Biology
13%
Negative Epistasis
13%
Sublethal Antibiotics
13%
Codon Composition
13%
Chromosomal Barcoding
13%
Biochemistry, Genetics and Molecular Biology
Dihydrofolate Reductase
87%
Enzyme
81%
Escherichia coli
68%
Methionine
43%
Drug Resistance
34%
Negative Selection (Natural Selection)
32%
Enzyme Activity
30%
Oligomerization
27%
Point Mutation
27%
Genotyping
26%
Metabolic Pathway
25%
Quality Control
24%
Horizontal Gene Transfer
23%
Trimethoprim Resistance
20%
Dynamics
19%
S-Adenosyl Methionine
18%
Cefotaxime
18%
Gene Library
18%
Active Site
17%
Antibiotic Resistance
17%
Protein-Protein Interaction
16%
Protein Homeostasis
16%
Proteome
15%
Subfunctionalization
13%
Neofunctionalization
13%
Protein Expression
13%
Reprogramming
13%
Mitochondrial Protein
13%
Ureaplasma
13%
Gene Duplication
13%
Protein Property
13%
Enterobacteria Phage T3
13%
Thymidine Monophosphate
13%
Thymidylate Kinase
13%
Peptide Sequence
13%
Gene Function
13%
Mutational Load
13%
Mitochondrion
13%
Homotetramer
13%
Chaperonin
13%
Metabolome
13%
Gene Dosage
13%
Nitrogen Metabolism
13%
Isocitrate Dehydrogenase
13%
Malate Dehydrogenase
13%
Codon
13%
Methyltransferase
13%
Protein Structure Prediction
13%
Antibiotic Resistance Gene
13%
Functional Genomics
13%