Organic Nanoparticles

During the grant period the research groups of Lemcoff and Zimmerman published 5 papers funded by and related to their joint BSF grant. Two papers were published in the prestigious journal Chemical Science and one in Angewandte Chemie, one in Chemical Reviews and the last one in ACS Nano; the references are cited herein. The joint work advanced the field of organic nanoparticles, especially related to their synthesis and functional applications, such as imaging and catalysis.

Prof. Zimmerman’s student Yugang Bai visited the laboratory of Prof. Lemcoff in Ben-Gurion University of the Negev for 3 weeks to work on the joint projects. At the beginning of the project Dr. Yuval Vidavsky from BGU visited the University of Illinois.

During the grant cycle Prof. Lemcoff and Prof. Zimmerman conducted several mutual meetings at the University of Illinois Urbana-Champaign and at Ben-Gurion University of the Negev to continue planning and expanding the successful cooperation between the groups.

The references for the published papers are:

1. Bai Y., Xing H., Vincil G. A., Lee J., Henderson E., Lu Y., Lemcoff N.G. and Zimmerman S. C.. Practical Synthesis of Water-soluble Organic Nanoparticles with a Single Reactive Group and a Functional Carrier Scaffold, Chemical Science, 2014, 5, 2862-2868.

2. Mavila, S.; Rozenberg, I.; Lemcoff, N.G. A general approach to mono- and bimetallic organometallic nanoparticles, Chemical Science, 2014, 5, 4196-4203.

3. Mavila S.; Diesendruck C.E.; Linde S.; Amir L.; Shikler R.; Lemcoff N.G. Polycyclooctadiene complexes of rhodium(I): direct access to organometallic nanoparticles, Angew. Chem. Int. Ed., 2013, 52, 5767-5770.

4. Mavila, S.; Eivgi, O.; Berkovich, I.; Lemcoff, N.G., Intramolecular Cross-Linking Methodologies for the Synthesis of Polymer Nanoparticles, Chemical Reviews, 2015, DOI: 10.1021/acs.chemrev.5b00290.

5. Yugang Bai, Hang Xing, Peiwen Wu, Xinxin Feng, Kevin Hwang, Jennifer M. Lee, Xin Yi Phang,Yi Lu, and Steven C. Zimmerman, Chemical Control over Cellular Uptake of Organic Nanoparticles by FineTuning Surface Functional Groups, ACS Nano, 2015, 9, 10227–10236.

As can be seen by the quality of the publications, the collaboration between the Zimmerman and Lemcoff groups is extremely successful. The renewal of the BSF grant will certainly allow to cement the scientific ties between the groups and produce even more fundamental advances in the field.