הגישה הזעיר פולשנית בכוויות: סקירת שלושים שנות מחקר ופיתוח תכשיר אנזימי להטריית כוויות

Translated title of the contribution: REVIEW OF 30 YEARS OF RESEARCH AND DEVELOPMENT OF AN ENZYMATIC DEBRIDEMENT AGENT FOR BURNS

יובל קריגר, ירון שהם, אלכסנדר בוגדנוב, אלדד זילברשטין, עמירם שגיא, אברהם לוי, ניר רוזנברג, גיא רובין, דנה אגוזי, יהודה אולמן, יוסף חיק, ליאור רוזנברג

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

INTRODUCTION: Early removal of burn eschar is a cornerstone of burn care. The most commonly practiced eschar removal technique for deep burns in modern burn care is surgical debridement but this technique is associated with surgical burden and leads to unnecessary excision of viable tissue.
GOALS: To review 30 years of research and development of an enzymatic debridement agent for burns.
METHODS: Studies performed during the last 30 years are reviewed in this manuscript.
RESULTS: Patients who underwent enzymatic debridement had a significantly shorter time to complete debridement, the surgical burden was significantly lower, hand burns did not necessitate escharotomy, and the long term results were favorable.
DISCUSSION: Early enzymatic debridement leads to an efficient debridement, preservation of viable tissue, a reduction in surgical burden and favorable long term results.
CONCLUSION: We believe early enzymatic debridement will lead to better care for burn victims and perhaps, even to a paradigm shift in the treatment of burns.
Translated title of the contributionREVIEW OF 30 YEARS OF RESEARCH AND DEVELOPMENT OF AN ENZYMATIC DEBRIDEMENT AGENT FOR BURNS
Original languageHebrew
Pages (from-to)281-285
Number of pages5
Journalהרפואה
Volume155
Issue number5
StatePublished - 1 May 2016

ASJC Scopus subject areas

  • Medicine (all)

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