3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial

Abraham Zangen; Mark George

doi:https://doi.org/10.1016/j.biopsych.2020.02.348

3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial

Abraham Zangen, Mark George

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.

Original language	English
Pages (from-to)	S129
Journal	Biological Psychiatry
Volume	87
Issue number	9 Supp.1
DOIs	https://doi.org/10.1016/j.biopsych.2020.02.348
State	Published - 7 May 2020

Keywords

Cigarette Smoking
Deep TMS
Drug Addiction

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

https://doi.org/10.1016/j.biopsych.2020.02.348

Cite this

@article{4c80fc7a81e84db2b88015ceee02982e,

title = "3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial",

abstract = "Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.",

keywords = "Cigarette Smoking, Deep TMS, Drug Addiction",

author = "Abraham Zangen and Mark George",

year = "2020",

month = may,

day = "7",

doi = "https://doi.org/10.1016/j.biopsych.2020.02.348",

language = "English",

volume = "87",

pages = "S129",

journal = "Biological Psychiatry",

issn = "0006-3223",

publisher = "Elsevier USA",

number = "9 Supp.1",

}

3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial. / Zangen, Abraham; George, Mark.
In: Biological Psychiatry, Vol. 87, No. 9 Supp.1, 07.05.2020, p. S129.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - 3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence

T2 - Results From an International, Multi-Site, Randomized, Sham Controlled Trial

AU - Zangen, Abraham

AU - George, Mark

PY - 2020/5/7

Y1 - 2020/5/7

N2 - Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.

AB - Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.

KW - Cigarette Smoking

KW - Deep TMS

KW - Drug Addiction

U2 - https://doi.org/10.1016/j.biopsych.2020.02.348

DO - https://doi.org/10.1016/j.biopsych.2020.02.348

M3 - Article

SN - 0006-3223

VL - 87

SP - S129

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 9 Supp.1

ER -

3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this