3-Weeks of Prefrontal and Insular Deep TMS Combined With Cue-Induced Craving Significantly Increases Smoking Abstinence: Results From an International, Multi-Site, Randomized, Sham Controlled Trial

Abraham Zangen, Mark George

Research output: Contribution to journalArticlepeer-review

Abstract

Tobacco smoking is the leading cause of preventable death in developed countries. Previous studies in animal models and humans suggest that repeated activation of cue-induced craving networks followed by electromagnetic stimulation of the prefrontal cortex (PFC) can cause lasting reductions in drug craving and consumption. This FDA pivotal double-blind sham-controlled multicenter study was designed to test the effectiveness of deep TMS to PFC and insula to induce smoking cessation.
Original languageEnglish
Pages (from-to)S129
JournalBiological Psychiatry
Volume87
Issue number9 Supp.1
DOIs
StatePublished - 7 May 2020

Keywords

  • Cigarette Smoking
  • Deep TMS
  • Drug Addiction

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