6β-hydroxy-Δ1-tetrahydrocannabinol synthesis and biological activity

Zvi Ben-Zvi; Raphael Mechoulam; Habib Edery; Gila Porath

doi:10.1126/science.174.4012.951

6β-hydroxy-Δ¹-tetrahydrocannabinol synthesis and biological activity

Zvi Ben-Zvi, Raphael Mechoulam, Habib Edery, Gila Porath

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

6β-Hydroxy-Δ1-tetrahydrocannabinol, a metabolite of Δ1-tetrahydrocannabinol has been synthesized from Δ6- tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this finding are discussed.

Original language	English
Pages (from-to)	951-952
Number of pages	2
Journal	Science
Volume	174
Issue number	4012
DOIs	https://doi.org/10.1126/science.174.4012.951
State	Published - 1 Jan 1971
Externally published	Yes

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title = "6β-hydroxy-Δ1-tetrahydrocannabinol synthesis and biological activity",

abstract = "6β-Hydroxy-Δ1-tetrahydrocannabinol, a metabolite of Δ1-tetrahydrocannabinol has been synthesized from Δ6- tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this finding are discussed.",

author = "Zvi Ben-Zvi and Raphael Mechoulam and Habib Edery and Gila Porath",

year = "1971",

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doi = "10.1126/science.174.4012.951",

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T1 - 6β-hydroxy-Δ1-tetrahydrocannabinol synthesis and biological activity

AU - Ben-Zvi, Zvi

AU - Mechoulam, Raphael

AU - Edery, Habib

AU - Porath, Gila

PY - 1971/1/1

Y1 - 1971/1/1

N2 - 6β-Hydroxy-Δ1-tetrahydrocannabinol, a metabolite of Δ1-tetrahydrocannabinol has been synthesized from Δ6- tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this finding are discussed.

AB - 6β-Hydroxy-Δ1-tetrahydrocannabinol, a metabolite of Δ1-tetrahydrocannabinol has been synthesized from Δ6- tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this finding are discussed.

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U2 - 10.1126/science.174.4012.951

DO - 10.1126/science.174.4012.951

M3 - Article

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SP - 951

EP - 952

JO - Science

JF - Science

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ER -

6β-hydroxy-Δ¹-tetrahydrocannabinol synthesis and biological activity

Abstract

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