A case-control study reveals immunoregulatory gene haplotypes that influence inhibitor risk in severe haemophilia A

Keyphrases

• Polymorphism 100%
• Interleukin-10 100%
• Severe Haemophilia A 100%
• Immunity Genes 100%
• Gene Haplotype 100%
• Hemophilia 66%
• Factor VIII Gene 66%
• Interleukin-12 (IL-12) 66%
• Factor VIII Inhibitor 66%
• Coding Sequence 33%
• Cytotoxic T-lymphocyte antigen-4 (CTLA-4) 33%
• Gene Coding 33%
• Th2 Cytokines 33%
• Immunomodulator 33%
• New Association 33%
• Gene Polymorphism 33%
• Inhibitor Development 33%
• Factor V Leiden 33%
• Rare Genotypes 33%
• HLA Haplotypes 33%
• Protective Haplotypes 33%
• Modifying Gene 33%
• Tag Single nucleotide Polymorphism (tSNP) 33%
• Non-inhibitor 33%
• Prothrombin 20210 33%

Immunology and Microbiology

• Haplotype 100%
• Factor VIII 83%
• Cytokine 33%
• Tumor Necrosis Factor 16%
• Single Nucleotide Polymorphism 16%
• Modifier Gene 16%
• Immunomodulating Drugs 16%
• DNA Polymorphism 16%