A compact CT/SPECT system for small-object imaging

Y. Zingerman; H. Golan; A. Gersten; A. Moalem

doi:10.1016/j.nima.2007.09.025

A compact CT/SPECT system for small-object imaging

Y. Zingerman, H. Golan, A. Gersten, A. Moalem

Department of Physics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We report herein on a low-cost, high-performance dual imaging modality CT/SPECT system for small objects or animals. The system is realized from a commercial micro-focus X-ray tube, a Gd2O2S:Tb phosphor screen and a CCD camera. SPECT/planar imaging is obtained using a pinhole collimator with the same camera module as for X-ray/CT. Fusion of anatomic and functional images from the two modalities is easily accomplished by adjusting the magnification of the two modalities. Using an X-ray tube of 15 μm focal spot size, an image magnification of 1:1500, a field of view of 110 mm×110 mm, and adopting variable gamma detection geometry, the system may serve for numerous imaging applications and can be expanded into high-sensitivity (300 cpm/μCi), sub-millimeter (0.86 mm) SPECT resolution over a field of view of 20 mm in diameter.

Original language	English
Pages (from-to)	135-148
Number of pages	14
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	584
Issue number	1
DOIs	https://doi.org/10.1016/j.nima.2007.09.025
State	Published - 1 Jan 2008

Keywords

CT/SPECT
Dual-modality system
Molecular imaging
Small-animal imaging
X-ray CCD detector

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

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10.1016/j.nima.2007.09.025

Cite this

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title = "A compact CT/SPECT system for small-object imaging",

abstract = "We report herein on a low-cost, high-performance dual imaging modality CT/SPECT system for small objects or animals. The system is realized from a commercial micro-focus X-ray tube, a Gd2O2S:Tb phosphor screen and a CCD camera. SPECT/planar imaging is obtained using a pinhole collimator with the same camera module as for X-ray/CT. Fusion of anatomic and functional images from the two modalities is easily accomplished by adjusting the magnification of the two modalities. Using an X-ray tube of 15 μm focal spot size, an image magnification of 1:1500, a field of view of 110 mm×110 mm, and adopting variable gamma detection geometry, the system may serve for numerous imaging applications and can be expanded into high-sensitivity (300 cpm/μCi), sub-millimeter (0.86 mm) SPECT resolution over a field of view of 20 mm in diameter.",

keywords = "CT/SPECT, Dual-modality system, Molecular imaging, Small-animal imaging, X-ray CCD detector",

author = "Y. Zingerman and H. Golan and A. Gersten and A. Moalem",

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doi = "10.1016/j.nima.2007.09.025",

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AU - Zingerman, Y.

AU - Golan, H.

AU - Gersten, A.

AU - Moalem, A.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - We report herein on a low-cost, high-performance dual imaging modality CT/SPECT system for small objects or animals. The system is realized from a commercial micro-focus X-ray tube, a Gd2O2S:Tb phosphor screen and a CCD camera. SPECT/planar imaging is obtained using a pinhole collimator with the same camera module as for X-ray/CT. Fusion of anatomic and functional images from the two modalities is easily accomplished by adjusting the magnification of the two modalities. Using an X-ray tube of 15 μm focal spot size, an image magnification of 1:1500, a field of view of 110 mm×110 mm, and adopting variable gamma detection geometry, the system may serve for numerous imaging applications and can be expanded into high-sensitivity (300 cpm/μCi), sub-millimeter (0.86 mm) SPECT resolution over a field of view of 20 mm in diameter.

AB - We report herein on a low-cost, high-performance dual imaging modality CT/SPECT system for small objects or animals. The system is realized from a commercial micro-focus X-ray tube, a Gd2O2S:Tb phosphor screen and a CCD camera. SPECT/planar imaging is obtained using a pinhole collimator with the same camera module as for X-ray/CT. Fusion of anatomic and functional images from the two modalities is easily accomplished by adjusting the magnification of the two modalities. Using an X-ray tube of 15 μm focal spot size, an image magnification of 1:1500, a field of view of 110 mm×110 mm, and adopting variable gamma detection geometry, the system may serve for numerous imaging applications and can be expanded into high-sensitivity (300 cpm/μCi), sub-millimeter (0.86 mm) SPECT resolution over a field of view of 20 mm in diameter.

KW - CT/SPECT

KW - Dual-modality system

KW - Molecular imaging

KW - Small-animal imaging

KW - X-ray CCD detector

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JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

IS - 1

ER -

A compact CT/SPECT system for small-object imaging

Abstract

Keywords

ASJC Scopus subject areas

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