A comparative matched analysis of clinical outcomes between transradial versus transfemoral percutaneous coronary intervention

Gabriel Greenberg, Tamir Bental, Eli I. Lev, Abid Assali, Hanna Vaknin-Assa, Ran Kornowski

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background: Several trials support the transradial route of percutaneous coronary intervention (PCI) since it reduces accesssite vascular complications and bleeding. Objectives: To examine the effects of transradial interventions (TRI) on clinical outcomes in a ‘real-world’ cohort of patients undergoing PCI. Methods: We analyzed 4873 consecutive patients who underwent PCI at a tertiary center and identified 373 patients who underwent TRI. Patients (radial vs. femoral) were compared using a propensity score analysis to best match between groups. Outcome parameters included total mortality, myocardial infarction (MI), repeat target vessel revascularization (TVR) rates, length of hospitalization and ΔHt/Hb/creatinine values during hospitalization. These were evaluated at 6 months and 1 to 3 years after PCI. Results: The rates of major adverse cardiovascular event (MACE) and its constituents were similar in the transradial vs. transfemoral groups at all time intervals: 6.7% vs. 5.5% at 6 months, 10.3% vs. 10% at 1 year, 15.7% vs. 15% at 2 years, 15.7% vs. 16% at 3 years, respectively (P = 0.6). The length of hospitalization was shorter in the TRI group (2.87 days ± 2.04 vs. 3.3 days ± 3.12, P = 0.023). We did not find significant differences between the groups in the mean ΔHt/Hb/creatinine values during the hospitalization course. Conclusions: In a real-world setting of PCI, the TRI route of PCI is as safe and efficient as the femoral approach. TRI is associated with shorter duration of hospitalization.

Original languageEnglish
Pages (from-to)360-364
Number of pages5
JournalIsrael Medical Association Journal
Issue number6
StatePublished - 1 Jun 2015
Externally publishedYes


  • Major adverse cardiovascular events (MACE)
  • Percutaneous coronary intervention (PCI)
  • Trans-radial intervention (TRI)
  • Transfemoral intervention (TFI)

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'A comparative matched analysis of clinical outcomes between transradial versus transfemoral percutaneous coronary intervention'. Together they form a unique fingerprint.

Cite this