A Comparison Between Two Screening Approaches for ASD Among Toddlers in Israel

Orly Kerub, Eric J. Haas, Gal Meiri, Nadav Davidovitch, Idan Menashe

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Systematic screening of autism spectrum disorder (ASD) can improve early diagnosis of ASD. We compared the efficacy of two ASD screening methods, the Global Developmental Screening (GDS), and the Modified Checklist for Autism in Toddlers-Revised, with Follow-Up (M-CHAT/F) in 1591 toddlers of ages 18–36 months from 35 government-funded clinics in south Israel. The M-CHAT/F performed better than the GDS in detecting toddlers with ASD (sensitivity: 70.0% vs. 50.0%, and specificity: 98.2% vs. 96.6% respectively). Both methods had an equivalent performance in detecting other forms of developmental delays (sensitivity = 63%; and specificity ~ 98%). In addition, remarkable inter-nurse variation was observed in the GDS referral decisions. Thus, employment of the M-CHAT/F in the Israeli health system may improve early detection of ASD among toddlers.

Original languageEnglish
Pages (from-to)1553-1560
Number of pages8
JournalJournal of Autism and Developmental Disorders
Issue number5
StatePublished - 1 May 2020


  • Autism spectrum disorder
  • M-CHAT
  • Screening
  • Toddlers

ASJC Scopus subject areas

  • Developmental and Educational Psychology


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