A convenient method for the synthesis of α-silylacetic acids

Alex V. Shtelman, James Y. Becker

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A method is described for the preparation of α-silylacetic acids of the type R3SiCH2CO2H by treating trimethylsilyl acetate with LDA followed by quenching with chlorosilanes.

Original languageEnglish
Pages (from-to)3101-3103
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number19
DOIs
StatePublished - 5 May 2008

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'A convenient method for the synthesis of α-silylacetic acids'. Together they form a unique fingerprint.

Cite this