A direct access to bioactive fused N-heterocyclic acetic acid derivatives

Raju Adepu; A. Rajitha; Dipali Ahuja; Atul Kumar Sharma; B. Ramudu; Ravikumar Kapavarapu; Kishore V.L. Parsa; Manojit Pal

doi:10.1039/c3ob42535e

A direct access to bioactive fused N-heterocyclic acetic acid derivatives

Raju Adepu, A. Rajitha, Dipali Ahuja, Atul Kumar Sharma, B. Ramudu, Ravikumar Kapavarapu, Kishore V.L. Parsa, Manojit Pal

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16 Scopus citations

Abstract

A Cu-catalyzed new sequence involving the Ullmann type intermolecular C-C followed by an intramolecular C-N coupling and then intramolecular aza-Michael type addition (and oxidation) in a single pot afforded various fused N-heterocyclic acetic acid derivatives as inhibitors of PDE4. This journal is

Original language	English
Pages (from-to)	2514-2518
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	12
Issue number	16
DOIs	https://doi.org/10.1039/c3ob42535e
State	Published - 28 Apr 2014
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c3ob42535e

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AU - Adepu, Raju

AU - Rajitha, A.

AU - Ahuja, Dipali

AU - Sharma, Atul Kumar

AU - Ramudu, B.

AU - Kapavarapu, Ravikumar

AU - Parsa, Kishore V.L.

AU - Pal, Manojit

PY - 2014/4/28

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AB - A Cu-catalyzed new sequence involving the Ullmann type intermolecular C-C followed by an intramolecular C-N coupling and then intramolecular aza-Michael type addition (and oxidation) in a single pot afforded various fused N-heterocyclic acetic acid derivatives as inhibitors of PDE4. This journal is

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A direct access to bioactive fused N-heterocyclic acetic acid derivatives

Abstract

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