A facile preparation of methyl indolylacetates via Stille carbonylation of n-protected bromomethylindocs

Neelamegam Ramesh, Vasudevan Dhayalan, Radhakrishnan Sureshbabu, Arasambattu K. Mohanakrishnan

Research output: Contribution to journalArticlepeer-review

Abstract

A systematic study on carbonylation of N-protected bromomethylindoles using different types of Pd catalyst and bases under Stille condition has been explored. Carbonylation of bromomethylindoles in the presence of methyl/ethyl alcohol led to the formation of the corresponding esters in reasonable yields.

Original languageEnglish
Pages (from-to)858-864
Number of pages7
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume48
Issue number6
StatePublished - 1 Jun 2009
Externally publishedYes

Keywords

  • Bromomethylindoles
  • Carbonylation
  • Indolylmethylesters
  • Pd catalyst

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • Organic Chemistry

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