A gain-scheduling model predictive controller for blood glucose control in type 1 diabetes

Amjad Abu-Rmileh, Winston Garcia-Gabin

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

This paper presents a control strategy for blood glucose (BG) level regulation in type 1 diabetic patients. To design the controller, model-based predictive control scheme has been applied to a newly developed diabetic patient model. The controller is provided with a feedforward loop to improve meal compensation, a gain-scheduling scheme to account for different BG levels, and an asymmetric cost function to reduce hypoglycemic risk. A simulation environment that has been approved for testing of artificial pancreas control algorithms has been used to test the controller. The simulation results show a good controller performance in fasting conditions and meal disturbance rejection, and robustness against model-patient mismatch and errors in meal estimation.

Original languageEnglish
Pages (from-to)2478-2484
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Volume57
Issue number10 PART 1
DOIs
StatePublished - 1 Oct 2010
Externally publishedYes

Keywords

  • Gain scheduling (GS)
  • Model predictive control (MPC)
  • Type 1 diabetes mellitus (T1DM)

ASJC Scopus subject areas

  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'A gain-scheduling model predictive controller for blood glucose control in type 1 diabetes'. Together they form a unique fingerprint.

Cite this