A general approach to N-heterocyclic carbenes with a fused tetracyclic core: Ligands for suzuki-miyaura cross-coupling reaction

Revannath L. Sutar; Vinod Kumar; Rahul D. Shingare; Shridhar Thorat; Rajesh Gonnade; D. Srinivasa Reddy

doi:10.1002/ejoc.201402378

A general approach to N-heterocyclic carbenes with a fused tetracyclic core: Ligands for suzuki-miyaura cross-coupling reaction

Revannath L. Sutar, Vinod Kumar, Rahul D. Shingare, Shridhar Thorat, Rajesh Gonnade, D. Srinivasa Reddy

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading.

Original language	English
Pages (from-to)	4482-4486
Number of pages	5
Journal	European Journal of Organic Chemistry
Volume	2014
Issue number	21
DOIs	https://doi.org/10.1002/ejoc.201402378
State	Published - 1 Jan 2014
Externally published	Yes

Keywords

C-C coupling
Carbenes
Homogeneous catalysis
N ligands
Synthetic methods

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/ejoc.201402378

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abstract = "The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading.",

keywords = "C-C coupling, Carbenes, Homogeneous catalysis, N ligands, Synthetic methods",

author = "Sutar, {Revannath L.} and Vinod Kumar and Shingare, {Rahul D.} and Shridhar Thorat and Rajesh Gonnade and Reddy, {D. Srinivasa}",

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T1 - A general approach to N-heterocyclic carbenes with a fused tetracyclic core

T2 - Ligands for suzuki-miyaura cross-coupling reaction

AU - Sutar, Revannath L.

AU - Kumar, Vinod

AU - Shingare, Rahul D.

AU - Thorat, Shridhar

AU - Gonnade, Rajesh

AU - Reddy, D. Srinivasa

PY - 2014/1/1

Y1 - 2014/1/1

N2 - The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading.

AB - The synthesis of an N-heterocyclic carbene (NHC) based on a tetracyclic scaffold by using simple, general, and scalable chemistry is disclosed. The developed route is suitable for introducing multiple substitutions on the tetracyclic scaffold. The utility of the present NHC as a ligand in the Suzuki-Miyaura cross-coupling reaction is demonstrated with a low catalyst loading.

KW - C-C coupling

KW - Carbenes

KW - Homogeneous catalysis

KW - N ligands

KW - Synthetic methods

UR - http://www.scopus.com/inward/record.url?scp=84904460245&partnerID=8YFLogxK

U2 - 10.1002/ejoc.201402378

DO - 10.1002/ejoc.201402378

M3 - Article

AN - SCOPUS:84904460245

SN - 1434-193X

VL - 2014

SP - 4482

EP - 4486

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 21

ER -

A general approach to N-heterocyclic carbenes with a fused tetracyclic core: Ligands for suzuki-miyaura cross-coupling reaction

Abstract

Keywords

ASJC Scopus subject areas

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