A model for the propagation of action potentials in non-uniformly excitable media

A. Rabinovitch, I. Aviram, N. Gulko, E. Ovsyshcher

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Electrophysiological properties of cardiac tissue change as a function of position. We define the 'excitability' as the propagation velocity of an excitation pulse through the tissue, and study a simple FitzHugh-Nagumo (FHN) model of heart tissue whose excitability changes with position. The propagation velocity is shown to be a good continuous measure of the excitability for both limit cycle and excitable tissues. The influence of the spatial dependence of the excitability is examined for several normal and pathological situations. A novel transient effect is observed for a train of pulses propagating across an excitability step.

Original languageEnglish
Pages (from-to)141-154
Number of pages14
JournalJournal of Theoretical Biology
Volume196
Issue number2
DOIs
StatePublished - 21 Jan 1999

Fingerprint

Dive into the research topics of 'A model for the propagation of action potentials in non-uniformly excitable media'. Together they form a unique fingerprint.

Cite this