A Non-Randomized Controlled Trial for Reducing Postpartum Depression in Low-Income Minority Women at Community-Based Women’s Health Clinics

Samira Alfayumi-Zeadna, Atif Zeadna, Zuya Azbarga, Lobna Salman, Miron Froimovici, Awad Alkatnany, Itamar Grotto, Nihaya Daoud

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objective: To analyze an intervention that delivered tailored clinic staff training on postpartum depression (PPD) followed by awareness raising and social support aimed at lowering PPD among low-income Bedouin women in southern Israel. Methods: We conducted a non-randomized controlled trial at two women’s health clinics. The study included 332 of the 384 eligible women recruited at baseline (intervention = 169, control = 163), who completed two face-to-face interviews, one at 26–38 weeks of pregnancy (Time 1) and one 2–4 months postpartum (Time 2). PPD was measured by the Edinburgh Postnatal Depression Scale (EPDS) and dichotomized using a ≥ 10 score cutoff. We calculated EPDS change (rate difference of dichotomous EPDS from Time 1 to Time 2) (no change, positive change, or negative change), and compared EPDS changes in a control clinic vs. an intervention clinic. Results: The intervention group showed a greater decrease in dichotomous EPDS ≥ 10 between times 1 and 2 (38.5% to 17.2%) than the control group (31.9% to 29.4%, PV = 0.008). Multinomial logistic regression showed that high PPD awareness significantly contributed to positive EPDS change in the intervention group (PV = 0.003) and high social support significantly protected against negative EPDS change in both groups, intervention (PV = 0.001) and control (PV = 0.003). Conclusions: In low-income women, an intervention focusing on increasing PPD awareness and social support following staff training was associated with reduced EPDS and positive EPDS change following the intervention. Similar interventions should be implemented in women’s clinics during pregnancy. Clinical Trial Registry: ClinicalTrials.gov NCT02862444.

Original languageEnglish
Pages (from-to)1689-1700
Number of pages12
JournalMaternal and Child Health Journal
Issue number8
Early online date21 Apr 2022
StateE-pub ahead of print - 21 Apr 2022


  • Bedouin women
  • Intervention
  • Low-income minority women
  • Non-randomized control trial
  • Postpartum depression

ASJC Scopus subject areas

  • Epidemiology
  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Public Health, Environmental and Occupational Health


Dive into the research topics of 'A Non-Randomized Controlled Trial for Reducing Postpartum Depression in Low-Income Minority Women at Community-Based Women’s Health Clinics'. Together they form a unique fingerprint.

Cite this