A novel approach for assessments of erythrocyte sedimentation rate

A. Pribush, L. Hatskelzon, N. Meyerstein

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Introduction: Previous studies have shown that the dispersed phase of sedimenting blood undergoes dramatic structural changes: Discrete red blood cell (RBC) aggregates formed shortly after a settling tube is filled with blood are combined into a continuous network followed by its collapse via the formation of plasma channels, and finally, the collapsed network is dispersed into individual fragments. Based on this scheme of structural transformation, a novel approach for assessments of erythrocyte sedimentation is suggested. Methods: Information about erythrocyte sedimentation is extracted from time records of the blood conductivity measured after a dispersion of RBC network into individual fragments. Results: It was found that the sedimentation velocity of RBC network fragments correlates positively with the intensity of attractive intercellular interactions, whereas no effect of hematocrit (Hct) was observed. Conclusion: Thus, unlike Westergren erythrocyte sedimentation rate, sedimentation data obtained by the proposed method do not require correction for Hct.

Original languageEnglish
Pages (from-to)251-257
Number of pages7
JournalInternational Journal of Laboratory Hematology
Issue number3
StatePublished - 1 Jun 2011


  • Aggregation
  • Conductivity
  • Erythrocyte
  • Sedimentation

ASJC Scopus subject areas

  • Hematology
  • Clinical Biochemistry
  • Biochemistry, medical


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