A novel method to improve prenatal diagnosis of abnormal systemic venous connections using three- and four-dimensional ultrasonography and 'inversion mode'

J. Espinoza, L. F. Gonçalves, W. Lee, M. Mazor, R. Romero

    Research output: Contribution to journalArticlepeer-review

    82 Scopus citations

    Abstract

    Objective: The precise prenatal diagnosis of abnormal venous connections of the fetal heart is challenging. Anatomical accuracy may be important in determining the best route for postnatal angiography, as well as the prognosis and treatment. This study was designed to determine the value of 'inversion mode', a new three- and four-dimensional (4D) rendering algorithm, in the visualization of the spatial relationships of an interrupted inferior vena cava (IVC) with azygos or hemiazygos vein continuation associated with and without heterotaxic syndromes. Methods: Heart volumes were acquired using 4D ultrasonography and spatiotemporal image correlation in cases of interrupted IVC with azygos/hemiazygos continuation (n = 3). Volume datasets were rendered using the 'inversion mode' algorithm and abnormal images were compared to those generated from a library of normal fetuses. Results: The 'inversion mode' rendering algorithm allowed the visualization of dilated azygos or hemiazygos veins and their spatial relationships with the descending aorta, the aortic arch, the superior vena cava, and the atria in cases of interrupted IVC with and without heterotaxic syndromes. Conclusions: The 'inversion mode' algorithm improves prenatal visualization of both dilated azygos and hemiazygos veins, as well as their spatial relationships with the surrounding vascular structures. This has implications for the accurate prenatal diagnosis and management of neonates with abnormal systemic venous connections.

    Original languageEnglish
    Pages (from-to)428-434
    Number of pages7
    JournalUltrasound in Obstetrics and Gynecology
    Volume25
    Issue number5
    DOIs
    StatePublished - 1 May 2005

    Keywords

    • 'inversion mode'
    • 3D/4D ultrasound
    • Azygos vein
    • Hemiazygos vein
    • STIC
    • Systemic venous connections

    ASJC Scopus subject areas

    • Radiological and Ultrasound Technology
    • Reproductive Medicine
    • Radiology Nuclear Medicine and imaging
    • Obstetrics and Gynecology

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