A phthalimidation protocol that follows protein defined parameters

Rohith Singudas, Srinivasa Rao Adusumalli, Pralhad Namdev Joshi, Vishal Rai

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


This work outlines the first phthalimidation protocol suitable for protein labeling and performed in aqueous media at room temperature and neutral pH with no catalyst or co-reagent required. The methodology is suitable for a range of amines and its efficiency was determined with chemoselective and site-selective protein labeling.

Original languageEnglish
Pages (from-to)473-476
Number of pages4
JournalChemical Communications
Issue number3
StatePublished - 11 Jan 2015
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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