A phthalimidation protocol that follows protein defined parameters

Rohith Singudas; Srinivasa Rao Adusumalli; Pralhad Namdev Joshi; Vishal Rai

doi:10.1039/c4cc08503e

A phthalimidation protocol that follows protein defined parameters

Rohith Singudas, Srinivasa Rao Adusumalli, Pralhad Namdev Joshi, Vishal Rai

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

This work outlines the first phthalimidation protocol suitable for protein labeling and performed in aqueous media at room temperature and neutral pH with no catalyst or co-reagent required. The methodology is suitable for a range of amines and its efficiency was determined with chemoselective and site-selective protein labeling.

Original language	English
Pages (from-to)	473-476
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	3
DOIs	https://doi.org/10.1039/c4cc08503e
State	Published - 11 Jan 2015
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c4cc08503e

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title = "A phthalimidation protocol that follows protein defined parameters",

abstract = "This work outlines the first phthalimidation protocol suitable for protein labeling and performed in aqueous media at room temperature and neutral pH with no catalyst or co-reagent required. The methodology is suitable for a range of amines and its efficiency was determined with chemoselective and site-selective protein labeling.",

author = "Rohith Singudas and Adusumalli, {Srinivasa Rao} and Joshi, {Pralhad Namdev} and Vishal Rai",

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AU - Singudas, Rohith

AU - Adusumalli, Srinivasa Rao

AU - Joshi, Pralhad Namdev

AU - Rai, Vishal

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/1/11

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AB - This work outlines the first phthalimidation protocol suitable for protein labeling and performed in aqueous media at room temperature and neutral pH with no catalyst or co-reagent required. The methodology is suitable for a range of amines and its efficiency was determined with chemoselective and site-selective protein labeling.

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JO - Chemical Communications

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A phthalimidation protocol that follows protein defined parameters

Abstract

ASJC Scopus subject areas

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