A prospective cohort study of the effect of vincristine on audition

Gilles Lugassy, Amnon Shapira

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We conducted a prospective cohort study of the possible ototoxic effect of vincristine among patients treated for lymphoproliferative malignancies. No deleterious effect of moderate doses of vincristine on pure tone audiometry for air and bone conduction and on speech audiometry could be found. Nevertheless, the isolated finding of sensorineural hearing loss in the only patient who received a high dose of vincristine raises the issue of ototoxicity as a possible dose-related and dose-limiting side effect of vincristine.

Original languageEnglish
Pages (from-to)525-526
Number of pages2
JournalAnti-Cancer Drugs
Issue number5
StatePublished - 1 Jan 1996


  • ototoxicity
  • vincristine

ASJC Scopus subject areas

  • Oncology
  • Pharmacology
  • Pharmacology (medical)
  • Cancer Research


Dive into the research topics of 'A prospective cohort study of the effect of vincristine on audition'. Together they form a unique fingerprint.

Cite this