A prospective cohort study of the effect of vincristine on audition

Gilles Lugassy, Amnon Shapira

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

We conducted a prospective cohort study of the possible ototoxic effect of vincristine among patients treated for lymphoproliferative malignancies. No deleterious effect of moderate doses of vincristine on pure tone audiometry for air and bone conduction and on speech audiometry could be found. Nevertheless, the isolated finding of sensorineural hearing loss in the only patient who received a high dose of vincristine raises the issue of ototoxicity as a possible dose-related and dose-limiting side effect of vincristine.

Original languageEnglish
Pages (from-to)525-526
Number of pages2
JournalAnti-Cancer Drugs
Volume7
Issue number5
DOIs
StatePublished - 1 Jan 1996

Keywords

  • ototoxicity
  • vincristine

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