Abstract
We conducted a prospective cohort study of the possible ototoxic effect of vincristine among patients treated for lymphoproliferative malignancies. No deleterious effect of moderate doses of vincristine on pure tone audiometry for air and bone conduction and on speech audiometry could be found. Nevertheless, the isolated finding of sensorineural hearing loss in the only patient who received a high dose of vincristine raises the issue of ototoxicity as a possible dose-related and dose-limiting side effect of vincristine.
| Original language | English |
|---|---|
| Pages (from-to) | 525-526 |
| Number of pages | 2 |
| Journal | Anti-Cancer Drugs |
| Volume | 7 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1 Jan 1996 |
Keywords
- ototoxicity
- vincristine
ASJC Scopus subject areas
- Oncology
- Pharmacology
- Pharmacology (medical)
- Cancer Research