A Recombitant Flavin-Adenine Dinucleotide Glucose Dehydrogenase and Uses Thereof

Lital Alfonta; Raz Zarivach; Jennifer Grushka; Itay Algov

A Recombitant Flavin-Adenine Dinucleotide Glucose Dehydrogenase and Uses Thereof

Lital Alfonta (Inventor)
, Raz Zarivach (Inventor)
, Jennifer Grushka (Inventor)
, Itay Algov (Inventor)

Research output: Patent

Abstract

A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.

Original language	English
Patent number	US2020165579
IPC	G01N 27/ 327 A I
Priority date	2/08/18
State	Published - 28 May 2020

Cite this

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abstract = "A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.",

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T1 - A Recombitant Flavin-Adenine Dinucleotide Glucose Dehydrogenase and Uses Thereof

AU - Alfonta, Lital

AU - Zarivach, Raz

AU - Grushka, Jennifer

AU - Algov, Itay

PY - 2020/5/28

Y1 - 2020/5/28

N2 - A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.

AB - A recombinant protein, including: (a) alpha subunit of an FAD-GDH; and (b) a minimal cytochrome c peptide is provided. Additionally, an electrode coupled to a recombinant protein, the recombinant protein made of: (a) a cofactor of a redox enzyme; (b) a redox enzyme; (c) a linker moiety configured to link any one of: the cofactor or the enzyme to an electron transfer (ET) domain; and (d) an ET domain, is also provided. Methods for: (a) transferring an electron to an electrode, by coupling the recombinant protein an electrode; and (b) quantifying the amount of an analyte e.g., glucose are also provided.

M3 - Patent

M1 - US2020165579

ER -

A Recombitant Flavin-Adenine Dinucleotide Glucose Dehydrogenase and Uses Thereof

Abstract

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