A review of randomized clinical trials of antibiotic therapy in preterm premature rupture of the membranes

E. Maymon, W. Chaim, E. Sheiner, M. Mazor

    Research output: Contribution to journalReview articlepeer-review

    26 Scopus citations

    Abstract

    Rupture of membranes before 37 completed weeks of gestation, and before the onset of contractions occurs among 2-3% of pregnancies, and in about 30%-40% of women who deliver preterm. It is known as preterm premature rupture of membranes (PPROM) and is associated with maternal and neonatal morbidity. It has been postulated that antibiotic therapy may significantly decrease the complications associated with infection. The aim of the present review is to summarize the available data about the value of antibiotic therapy in PPROM.

    Original languageEnglish
    Pages (from-to)173-181
    Number of pages9
    JournalArchives of Gynecology and Obstetrics
    Volume261
    Issue number4
    DOIs
    StatePublished - 1 Aug 1998

    Keywords

    • Antibiotic therapy
    • Infant morbidity
    • Maternal morbidity
    • Preterm premature rupture of membranes

    ASJC Scopus subject areas

    • Obstetrics and Gynecology

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