A study of the external exposure decay curves as a function of several clinical parameters for patients treated with therapeutic131I

Dimitry Ginzburg, Sophia Lantsberg, Sergio Faermann

Research output: Contribution to journalArticlepeer-review

Abstract

Hyperthyroid and thyroid carcinoma patients treated with radioactive 131I (RAI) are a potential source of external and internal exposure to members of the public, to medical staff and especially to family members, who are in close contact with these patients. The relationship between radiation dose rates and various clinical parameters, including gender, age, thyroid size and weight, and iodine uptake, was assessed. Dose rates were measured on eight patients with thyroid carcinoma after total or subtotal thyroidectomy and on six patients with hyperthyroidism. All measurements were taken at 1 m from the patient on two levels—anterior to the neck and body center. Dose rates were measured at three or four times—at the time of RAI administration, and after 24 h, 48 h, and 168 h. Based on these measurements, retention curves were obtained. The effective half-life was derived by fitting an exponential equation and was estimated to be 12.8 h.

Original languageEnglish
Article number030906-1
JournalJournal of Nuclear Engineering and Radiation Science
Volume3
Issue number3
DOIs
StatePublished - 1 Jul 2017
Externally publishedYes

ASJC Scopus subject areas

  • Radiation
  • Nuclear Energy and Engineering

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