A Three-Component Synthesis of Spiropyrrolines

Kanchanbala Sahoo; Nityaprakash Patra; Rambabu Dandela; Barla Thirupathi

doi:10.1021/acs.joc.3c02713

A Three-Component Synthesis of Spiropyrrolines

Kanchanbala Sahoo, Nityaprakash Patra, Rambabu Dandela, Barla Thirupathi

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.

Original language	English
Pages (from-to)	5337-5352
Number of pages	16
Journal	Journal of Organic Chemistry
Volume	89
Issue number	8
DOIs	https://doi.org/10.1021/acs.joc.3c02713
State	Published - 19 Apr 2024
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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10.1021/acs.joc.3c02713

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title = "A Three-Component Synthesis of Spiropyrrolines",

abstract = "A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.",

author = "Kanchanbala Sahoo and Nityaprakash Patra and Rambabu Dandela and Barla Thirupathi",

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AU - Sahoo, Kanchanbala

AU - Patra, Nityaprakash

AU - Dandela, Rambabu

AU - Thirupathi, Barla

PY - 2024/4/19

Y1 - 2024/4/19

N2 - A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.

AB - A rapid synthesis of medicinally important spiropyrrolines has been achieved by the reaction of 1,3-indanediones, benzaldehyde, and (1-azidovinyl)benzene under catalyst- and reagent-free conditions. This is the first report to synthesize diverse spiropyrroline compounds from readily available feedstock materials under metal-free conditions.

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U2 - 10.1021/acs.joc.3c02713

DO - 10.1021/acs.joc.3c02713

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SP - 5337

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

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A Three-Component Synthesis of Spiropyrrolines

Abstract

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