Abstract
Background: Acanthosis nigricans and hyperandrogenism have been associated with diabetes mellitus accompanied by insulin resistance. However, these manifestations have rarely been reported to occur as a result of the insulin resistance of pregnancy. Case: A 31-year-old woman with diabetes mellitus exhibited severe insulin resistance during pregnancy. At 32 weeks, daily administration of 500 U insulin was required to maintain glycemic control. Skin lesions typical of acanthosis nigricans appeared, and free testosterone levels were elevated (10.3 pg/mL). These manifestations resolved after delivery. Conclusion: This case may demonstrate a correlation between reversible gestational insulin resistance and acanthosis nigricans.
| Original language | English |
|---|---|
| Pages (from-to) | 810-811 |
| Number of pages | 2 |
| Journal | Obstetrics and Gynecology |
| Volume | 81 |
| Issue number | 5 |
| State | Published - 1 Jan 1993 |
ASJC Scopus subject areas
- Obstetrics and Gynecology
