Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy

M. Abu-Shakra, P. Nicol, M. B. Urowitz

    Research output: Contribution to journalArticlepeer-review

    42 Scopus citations

    Abstract

    We describe a patient with seropositive erosive rheumatoid arthritis (RA) who developed accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate (MTX) therapy while her arthritis remained inactive. MTX is an effective therapy for the articular manifestations of RA. However, on occasion it may result in triggering the development of extraarticular manifestations of RA.

    Original languageEnglish
    Pages (from-to)934-937
    Number of pages4
    JournalJournal of Rheumatology
    Volume21
    Issue number5
    StatePublished - 1 Jan 1994

    Keywords

    • Extraarticular features
    • Methotrexate
    • Rheumatoid arthritis

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Rheumatology
    • Immunology

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