Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox

Galina Ling, Vered Pinsk, Inbal Golan-Tripto, Eduard Ling

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.

Original languageEnglish
Article number5987
Pages (from-to)74-76
Number of pages3
JournalHematology Reports
Volume7
Issue number3
DOIs
StatePublished - 23 Sep 2015
Externally publishedYes

Keywords

  • Acute liver failure
  • Congenital dyserythropoietic anemia
  • Deferasirox
  • N-acetylcysteine

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