Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox

Galina Ling; Vered Pinsk; Inbal Golan-Tripto; Eduard Ling

doi:10.4081/hr.2015.5987

Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox

Galina Ling, Vered Pinsk, Inbal Golan-Tripto, Eduard Ling

Medical School for International Health

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.

Original language	English
Article number	5987
Pages (from-to)	74-76
Number of pages	3
Journal	Hematology Reports
Volume	7
Issue number	3
DOIs	https://doi.org/10.4081/hr.2015.5987
State	Published - 23 Sep 2015

Keywords

Acute liver failure
Congenital dyserythropoietic anemia
Deferasirox
N-acetylcysteine

ASJC Scopus subject areas

Hematology

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10.4081/hr.2015.5987

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title = "Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox",

abstract = "Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.",

keywords = "Acute liver failure, Congenital dyserythropoietic anemia, Deferasirox, N-acetylcysteine",

author = "Galina Ling and Vered Pinsk and Inbal Golan-Tripto and Eduard Ling",

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AU - Ling, Galina

AU - Pinsk, Vered

AU - Golan-Tripto, Inbal

AU - Ling, Eduard

N1 - Publisher Copyright: © G. Ling et al., 2015 Licensee PAGEPress, Italy.

PY - 2015/9/23

Y1 - 2015/9/23

N2 - Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.

AB - Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.

KW - Acute liver failure

KW - Congenital dyserythropoietic anemia

KW - Deferasirox

KW - N-acetylcysteine

UR - https://www.scopus.com/pages/publications/84942235386

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DO - 10.4081/hr.2015.5987

M3 - Article

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IS - 3

M1 - 5987

ER -

Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox

Abstract

Keywords

ASJC Scopus subject areas

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