Acute lymphoblastic leukemia with T(4;11) translocation after osteogenic sarcoma

Joseph Kapelushnik, Ian Dubé, Peter Wilson, Mark Greenberg

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


The authors report a case of acute lymphoblastic leukemia (ALL) with t(4;11) (q21;q23) occurring 9 months after treatment of osteogenic sarcoma. Cell surface marker and molecular analyses suggest early B lineage involvement. This is the first report, to the knowledge of the authors, of t(4;11) ALL arising after an osteogenic sarcoma. The observations of the authors support the possibility of a causal relationship between exposure to carcinogens and the occurrence of leukemia with t(4;11).

Original languageEnglish
Pages (from-to)2887-2889
Number of pages3
Issue number11
StatePublished - 1 Jan 1991
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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