Acute myo-inositol enhances swimming activity in goldfish

J. Levine, K. N.R. Chengappa, R. Reddy

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Inositol in concentrations of 1-4 Mm (but not the control condition: mannitol-glucose) administered in aquarium water showed enhancement of swimming activity of goldfish after acute treatment (5 hours). These data support similar findings in rats. These data suggest that inositol may enhance motor activity which may be of relevance in neuropsychiatric disorders. Future studies of the effects of lithium on this activity, and its potential reversal by inositol may shed light on the possible involvement of the phosphatidyl-inositol second messenger system in this behavior.

Original languageEnglish
Pages (from-to)433-441
Number of pages9
JournalJournal of Neural Transmission
Volume106
Issue number5-6
DOIs
StatePublished - 1 Jan 1999
Externally publishedYes

Keywords

  • Goldfish
  • Inositol
  • Swimming

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry

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