Acute pancreatitis in childhood: Research of pathogenesis and clinical implications

Acute pancreatitis in children is more common than has previously been considered. A recent literature analysis has demonstrated significant resulting morbidity and mortality. Clinical awareness has improved dramatically, as demonstrated by the increase in the number of recent: publications and etiological considerations. This review describes novel considerations in research related to the pathogenesis of acute pancreatitis and the arising clinical implications. This relationship is discussed regarding a better understanding of pathogenesis in pediatric disorders; increasing awareness; preventing damage by drugs and toxins; using novel diagnostic markers; and introducing new therapeutic tools.