TY - JOUR
T1 - Adenocarcinoma of the uterine cervix
T2 - A study of 37 cases
AU - Piura, Benjamin
AU - Dgani, Ram
AU - Yanai-Inbar, Ilana
AU - Cohen, Yoram
AU - Glezerman, Marek
PY - 1996/4/1
Y1 - 1996/4/1
N2 - In a study of 37 patients diagnosed with cervical adenocarcinoma between 1961 and 1994, clinical and pathologic findings were evaluated. Of the 37 patients, 27 (73%) had a pure adenocarcinoma, five (13.5%) had a collision tumor and five (13.5%) had an adenosquamous carcinoma. Twenty-six patients (70.3%) were diagnosed in Stage I, and II (29.7%) patients in Stage II, III, and IV. Two patients (5.4%) were treated with simple hysterectomy alone, nine (24.3%) with simple hysterectomy followed by radiotherapy, eight (21.6%) with radical hysterectomy alone, five (13.5%) with radical hysterectomy followed by radiotherapy, nine (24.3%) with radiotherapy alone, one (2.7%) with radiotherapy followed by simple hysterectomy, and three (8.1%) received no treatment. The actuarial 5-year survival rate was 69%. It is suggested that for patients with small early-stage disease, radical hysterectomy should be primary treatment and postoperative adjuvant radiotherapy would be advocated if high-risk features are histologically demonstrated. For all other patients, radiotherapy should be primary treatment.
AB - In a study of 37 patients diagnosed with cervical adenocarcinoma between 1961 and 1994, clinical and pathologic findings were evaluated. Of the 37 patients, 27 (73%) had a pure adenocarcinoma, five (13.5%) had a collision tumor and five (13.5%) had an adenosquamous carcinoma. Twenty-six patients (70.3%) were diagnosed in Stage I, and II (29.7%) patients in Stage II, III, and IV. Two patients (5.4%) were treated with simple hysterectomy alone, nine (24.3%) with simple hysterectomy followed by radiotherapy, eight (21.6%) with radical hysterectomy alone, five (13.5%) with radical hysterectomy followed by radiotherapy, nine (24.3%) with radiotherapy alone, one (2.7%) with radiotherapy followed by simple hysterectomy, and three (8.1%) received no treatment. The actuarial 5-year survival rate was 69%. It is suggested that for patients with small early-stage disease, radical hysterectomy should be primary treatment and postoperative adjuvant radiotherapy would be advocated if high-risk features are histologically demonstrated. For all other patients, radiotherapy should be primary treatment.
KW - high-risk histologic features
KW - ovarian conservation
KW - radical hysterectomy
KW - radiotherapy
KW - simple hysterectomy
KW - vaginal bleeding
UR - http://www.scopus.com/inward/record.url?scp=0029921629&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1096-9098(199604)61:4<249::AID-JSO3>3.0.CO;2-A
DO - 10.1002/(SICI)1096-9098(199604)61:4<249::AID-JSO3>3.0.CO;2-A
M3 - Article
AN - SCOPUS:0029921629
SN - 0022-4790
VL - 61
SP - 249
EP - 255
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 4
ER -