Affecting Peptides Folding and Functionality within Synthetic Networks by External Triggers

S Alasibi, G Ashkenasy

Research output: Contribution to journalMeeting Abstract

Abstract

Various factors can affect the conformations and folding
states of protein molecules and as a consequence their
activity. These factors include amino acid mutations,
interactions with other macromolecules, binding to
regulatory molecules, and also external changes such as
pH jump or shining light. In order to control the folding
states and to modulate the functions of peptides and
proteins by light, photocleavable groups are usually
incorporated into specific residues to mask critical
interactions.
Original languageEnglish
Article numberP379
Pages (from-to)S194-S194
Number of pages1
JournalJournal of Peptide Science
Volume18
Issue numberS1
DOIs
StatePublished - Aug 2012

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