Ageing of lymphocytes and lymphocytes in the aged

Amiela Globerson, Rita B. Effros

Research output: Contribution to journalReview articlepeer-review

273 Scopus citations

Abstract

Immunosenescence is a complex process involving multiple reorganizational and developmentally regulated changes, rather than simple unidirectional decline in all functions. Here, these compensatory modulations are reviewed with reference to the importance of integrating information on cellular alterations identified in vitro with data on global physiological changes in the aged environment with which these cells interact in vivo.

Original languageEnglish
Pages (from-to)515-521
Number of pages7
JournalImmunology Today
Volume21
Issue number10
DOIs
StatePublished - 30 Oct 2000
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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