AlCl3 mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Bagineni Prasad; Raju Adepu; Sandhya Sandra; D. Rambabu; G. Rama Krishna; C. Malla Reddy; Girdhar Singh Deora; Parimal Misra; Manojit Pal

doi:10.1039/c2cc35757g

AlCl₃ mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Bagineni Prasad, Raju Adepu, Sandhya Sandra, D. Rambabu, G. Rama Krishna, C. Malla Reddy, Girdhar Singh Deora, Parimal Misra, Manojit Pal

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl₃ mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.

Original language	English
Pages (from-to)	10434-10436
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	84
DOIs	https://doi.org/10.1039/c2cc35757g
State	Published - 26 Sep 2012
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1039/c2cc35757g

Cite this

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abstract = "A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.",

author = "Bagineni Prasad and Raju Adepu and Sandhya Sandra and D. Rambabu and Krishna, {G. Rama} and Reddy, {C. Malla} and Deora, {Girdhar Singh} and Parimal Misra and Manojit Pal",

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AU - Prasad, Bagineni

AU - Adepu, Raju

AU - Sandra, Sandhya

AU - Rambabu, D.

AU - Krishna, G. Rama

AU - Reddy, C. Malla

AU - Deora, Girdhar Singh

AU - Misra, Parimal

AU - Pal, Manojit

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AB - A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.

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