AlCl3 mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Bagineni Prasad; Raju Adepu; Sandhya Sandra; D. Rambabu; G. Rama Krishna; C. Malla Reddy; Girdhar Singh Deora; Parimal Misra; Manojit Pal

doi:10.1039/c2cc35757g

AlCl₃ mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Bagineni Prasad
, Raju Adepu
, Sandhya Sandra
, D. Rambabu
, G. Rama Krishna
, C. Malla Reddy
, Girdhar Singh Deora
, Parimal Misra
, Manojit Pal

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl₃ mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.

Original language	English
Pages (from-to)	10434-10436
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	84
DOIs	https://doi.org/10.1039/c2cc35757g
State	Published - 26 Sep 2012
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c2cc35757g

Cite this

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title = "AlCl3 mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest",

abstract = "A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.",

author = "Bagineni Prasad and Raju Adepu and Sandhya Sandra and D. Rambabu and Krishna, \{G. Rama\} and Reddy, \{C. Malla\} and Deora, \{Girdhar Singh\} and Parimal Misra and Manojit Pal",

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language = "English",

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pages = "10434--10436",

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T2 - Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

AU - Prasad, Bagineni

AU - Adepu, Raju

AU - Sandra, Sandhya

AU - Rambabu, D.

AU - Krishna, G. Rama

AU - Reddy, C. Malla

AU - Deora, Girdhar Singh

AU - Misra, Parimal

AU - Pal, Manojit

PY - 2012/9/26

Y1 - 2012/9/26

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AB - A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.

UR - https://www.scopus.com/pages/publications/84866893348

U2 - 10.1039/c2cc35757g

DO - 10.1039/c2cc35757g

M3 - Article

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AN - SCOPUS:84866893348

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JF - Chemical Communications

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